Tubb4b Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Tubb4b
tubulin, beta 4B class IVB
MGI:1915472

25 phenotypes from 4 alleles in 5 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Tubb4b^em1(IMPC)J/Tubb4b⁺ C57BL/6NJ-Tubb4b^em1(IMPC)J/Mmjax	abnormal coat appearance	J:211773
Tubb4b^em1(IMPC)J/Tubb4b⁺ C57BL/6NJ-Tubb4b^em1(IMPC)J/Mmjax	abnormal coat/ hair morphology	J:211773
Tubb4b^em1(IMPC)J/Tubb4b^em1(IMPC)J C57BL/6NJ-Tubb4b^em1(IMPC)J/Mmjax	preweaning lethality, incomplete penetrance	J:211773
Tubb4b^em1(IMPC)J/Tubb4b^em1(IMPC)J involves: 129S/SvEv * C57BL/6NJ	abnormal Deiters cell morphology	J:354347
	abnormal motile cilium morphology	J:354347
	abnormal pillar cell morphology	J:354347
	abnormal spermatocyte morphology	J:354352
	azoospermia	J:354352
	deafness	J:354347
	decreased distortion product otoacoustic emission amplitude	J:354347
	decreased testis weight	J:354352
	normal hearing/vestibular/ear phenotype	J:354347
	increased susceptibility to otitis media	J:354347
	male infertility	J:354352
	normal nervous system phenotype	J:354347
	seminiferous tubule degeneration	J:354352
	small testis	J:354352
	normal vision/eye phenotype	J:354347
Tubb4b^em1Visu/Tubb4b⁺ C57BL/6J-Tubb4b^em1Visu	abnormal spermatocyte morphology	J:354352
	azoospermia	J:354352
	decreased testis weight	J:354352
	increased Leydig cell number	J:354352
	male infertility	J:354352
	small testis	J:354352
Tubb4b^em2Visu/Tubb4b^em2Visu C57BL/6J-Tubb4b^em2Visu	normal vision/eye phenotype	J:354347
Tubb4b^{tm2b(EUCOMM)Wtsi}/Tubb4b^{tm2b(EUCOMM)Wtsi} involves: C57BL/6 * FVB	abnormal branching involved in lung morphogenesis	J:344732
	abnormal oviduct epithelium motile cilium morphology	J:344732
	abnormal respiratory motile cilium morphology	J:344732
	hydrocephaly	J:344732
	postnatal growth retardation	J:344732
	postnatal lethality, incomplete penetrance	J:344732
	normal vision/eye phenotype	J:344732

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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