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Mettl21a Gene Detail
Summary
  • Symbol
    Mettl21a
  • Name
    methyltransferase like 21A
  • Synonyms
    2310038H17Rik, Fam119a
  • Feature Type
    protein coding gene
  • IDs
    MGI:1914349
    NCBI Gene: 67099
  • Alliance
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr1:64606473-64617242 bp, - strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 1, 32.74 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    58 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1914349
protein coding gene Chr1:64606473-64618552 (-)
129S1/SvImJ MGP_129S1SvImJ_G0016096
protein coding gene Chr1:64783744-64794538 (-)
A/J MGP_AJ_G0016079
protein coding gene Chr1:62501757-62512549 (-)
AKR/J MGP_AKRJ_G0016036
protein coding gene Chr1:64249325-64260111 (-)
BALB/cJ MGP_BALBcJ_G0016034
protein coding gene Chr1:62596388-62607157 (-)
C3H/HeJ MGP_C3HHeJ_G0015866
protein coding gene Chr1:64528284-64539078 (-)
C57BL/6NJ MGP_C57BL6NJ_G0016487
protein coding gene Chr1:67290816-67302921 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0014208
protein coding gene Chr1:58556959-58568070 (-)
CAST/EiJ MGP_CASTEiJ_G0015449
protein coding gene Chr1:63790977-63800700 (-)
CBA/J MGP_CBAJ_G0015838
protein coding gene Chr1:69480082-69491882 (-)
DBA/2J MGP_DBA2J_G0015939
protein coding gene Chr1:61907200-61917991 (-)
FVB/NJ MGP_FVBNJ_G0015942
protein coding gene Chr1:61184973-61195649 (-)
LP/J MGP_LPJ_G0016011
protein coding gene Chr1:65686690-65697484 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0015962
protein coding gene Chr1:72345261-72356784 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0016534
protein coding gene Chr1:64232795-64244885 (-)
PWK/PhJ MGP_PWKPhJ_G0015236
protein coding gene Chr1:61290351-61301475 (-)
SPRET/EiJ MGP_SPRETEiJ_G0015015
protein coding gene Chr1:63722327-63734725 (-)
WSB/EiJ MGP_WSBEiJ_G0015511
protein coding gene Chr1:63940031-63950806 (-)



Homology
more
  • Human Ortholog
    METTL21A, methyltransferase like 21A
  • Vertebrate Orthologs
    10
  • Human Ortholog
    METTL21A, methyltransferase like 21A
    Orthology source: HomoloGene, HGNC
  • Synonyms
    FAM119A, HCA557b, HSPA-KMT
  • Links
    NCBI Gene ID: 151194
    neXtProt AC: NX_Q8WXB1
    UniProt: Q8WXB1

  • Chr Location
    2q33.3; chr2:207580631-207625928 (-)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    8 phenotype references
  • All Mutations and Alleles
    7
  • Chemically induced (other)
    1
  • Gene trapped
    4
  • Radiation induced
    1
  • Targeted
    1
  • Genomic Mutations
    2 involving Mettl21a
  • Find Mice (IMSR)
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000025956 Ensembl Gene Model | MGI Sequence Detail 10770 C57BL/6J ±  kb
transcript ENSMUST00000114079 Ensembl | MGI Sequence Detail 2030 Not Applicable  
polypeptide ENSMUSP00000109713 Ensembl | MGI Sequence Detail 218 Not Applicable  
For the selected sequence
Protein
Information
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  • UniProt
    1 Sequence
  • EC
  • InterPro Domains
    IPR019410 Lysine methyltransferase
    IPR029063 S-adenosyl-L-methionine-dependent methyltransferase
Molecular
Reagents
less
  • All nucleic 30
    cDNA 30

    Microarray probesets 6
Other
Accession IDs
less
MGI:2138265
References
more
  • Summaries
    All 29
    Developmental Gene Expression 1
    Gene Ontology 2
    Phenotypes 8
  • Earliest
    J:134667 Roderick TH, et al., Two radiation-induced chromosomal inversions in mice (Mus musculus). Proc Natl Acad Sci U S A. 1970 Oct;67(2):961-7
  • Latest
    J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
03/13/2019
MGI 6.13
The Jackson Laboratory