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Lztr1
Gene Detail
 Symbol
Name
ID
Lztr1
leucine-zipper-like transcriptional regulator, 1
MGI:1914113
Synonyms 1200003E21Rik, TCFL2
Feature Type protein coding gene
Genetic Map
Chromosome 16
10.85 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr16:17508688-17526333 bp, + strand
From VEGA annotation of GRCm38

  17646 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:4925  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

Gene Tree: Lztr1

Human
homologs
Human Homolog LZTR1, leucine-zipper-like transcription regulator 1
NCBI Gene ID 8216
neXtProt AC  NX_Q8N653
Human Synonyms  BTBD29, LZTR-1, SWNTS2
Human Chr (Location)  22q11.21; chr22:20982269-20999037 (+)  GRCh38
Disease Associations  (1) Diseases Associated with Human LZTR1
Mutations,
alleles, and
phenotypes
All mutations/alleles(7) : Gene trapped(5) Targeted(2)
Incidental mutations (data from Mutagenetix , APF )
Interactions
Lztr1 interacts with 109 markers (Mir15a, Mir17, Mir20b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (3 annotations)
Process biological_process
Component cellular_component
Function molecular_function
External Resources: FuncBase
Expression
Literature Summary: (6 records)
Data Summary: Results (232)    Tissues (185)    Images (40)
Theiler Stages: 2, 3, 4, 5, 9, 10, 11, 13, 15, 17, 21, 22, 23, 27, 28
Assay TypeResults
RNA in situ 224
RT-PCR 8
cDNA source data(14)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(16) cDNA(14) Primer pair(2)
Microarray probesets(4)
Other database
links
VEGA Gene ModelOTTMUSG00000025194 (Evidence)
Ensembl Gene ModelENSMUSG00000022761 (Evidence)
Entrez Gene66863 (Evidence)
DFCITC1572381, TC1596900, TC1751461
DoTSDT.101409027, DT.531711, DT.55110380, DT.91556345, DT.94351159, DT.99738546
NIA Mouse Gene IndexU016874
Consensus CDS ProjectCCDS37272.1
International Mouse Knockout Project StatusLztr1
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000025194 VEGA Gene Model | MGI Sequence Detail 17646 C57BL/6J ±  kb
transcript OTTMUST00000062025 VEGA | MGI Sequence Detail 3394 Not Applicable 
polypeptide OTTMUSP00000030527 VEGA | MGI Sequence Detail 837 Not Applicable 

For the selected sequences
All sequences(74) RefSeq(6) UniProt(4)
Polymorphisms SNPs within 2kb(88 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR013069 BTB/POZ
InterPro IPR011333 BTB/POZ fold
InterPro IPR000210 BTB/POZ-like
InterPro IPR006652 Kelch repeat type 1
InterPro IPR015915 Kelch-type beta propeller
Protein Ontology PR:000010020 leucine-zipper-like transcriptional regulator 1
References (Earliest) J:28008 Harrison SM, et al., Isolation of novel tissue-specific genes from cDNA libraries representing the individual tissue constituents of the gastrulating mouse embryo. Development. 1995 Aug;121(8):2479-89
(Latest) J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
All references(41)
Other
accession IDs
MGI:2146460, MGI:2146657

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
09/09/2014
MGI 5.19
The Jackson Laboratory