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Foxp1
Gene Detail
Symbol

Name
ID
Foxp1
forkhead box P1
MGI:1914004
Synonyms
3110052D19Rik, 4932443N09Rik
Feature Type
protein coding gene
Genetic Map
Chromosome 6
45.74 cM, cytoband E1
Detailed Genetic Map ± 1 cM


Mapping data(5)
Sequence Map
Chr6:98925338-99522721 bp, - strand
From VEGA annotation of GRCm38

  597384 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:13092  Vertebrate Homology Class
1 mouse; 1 rat; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 zebrafish

Gene Tree: Foxp1

Mutations,
alleles, and
phenotypes
All mutations/alleles(45) : Gene trapped(39) Targeted(6)
Incidental mutations (data from Mutagenetix , APF )
 
Homozygous null mice display embryonic lethality with abnormal outflow tract septation, ventricular septal defects, abnormal cardiac valve morphology, decreased and irregular heart rate, thin ventricular compact zone, and edema.
 
Interactions
Foxp1 interacts with 463 markers (Mir1a-1, Mir1a-2, Mir7-1, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (46 annotations)
Process cardiac muscle cell differentiation, cardiovascular system development, ...
Component nucleus
Function chromatin binding, DNA binding, ...
External Resources: FuncBase
Expression
Literature Summary: (79 records)
Data Summary: Results (213)    Tissues (98)    Images (46)    Tissue x Stage Matrix (view)
Assay TypeResults
Immunohistochemistry 18
RNA in situ 160
Northern blot 16
RT-PCR 19
cDNA source data(33)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(38) cDNA(34) Primer pair(4)
Microarray probesets(8)
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000022717 VEGA Gene Model | MGI Sequence Detail 597384 C57BL/6J ±  kb
transcript OTTMUST00000054485 VEGA | MGI Sequence Detail 2121 Not Applicable 
polypeptide OTTMUSP00000026014 VEGA | MGI Sequence Detail 706 Not Applicable 

For the selected sequences
All sequences(251) RefSeq(40) UniProt(41)
Polymorphisms
SNPs within 2kb(2429 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR001766 Transcription factor, fork head
InterPro IPR018122 Transcription factor, fork head, conserved site
InterPro IPR011991 Winged helix-turn-helix DNA-binding domain
InterPro IPR015880 Zinc finger, C2H2-like
Protein Ontology PR:000007643 forkhead box protein P1
References
(Earliest) J:93290 Araki K, et al., Exchangeable gene trap using the Cre/mutated lox system. Cell Mol Biol (Noisy-le-grand). 1999 Jul;45(5):737-50
(Latest) J:213871 Li X, et al., Sp8 plays a supplementary role to Pax6 in establishing the pMN/p3 domain boundary in the spinal cord. Development. 2014 Jul;141(14):2875-84
All references(128)
Other
accession IDs
MGI:1889841, MGI:1920481, MGI:2141684

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
12/16/2014
MGI 5.20
The Jackson Laboratory