|Human Homolog||LRAT, lecithin retinol acyltransferase (phosphatidylcholine--retinol O-acyltransferase)|
|NCBI Gene ID||9227|
|Human Chr (Location)||4q32.1; chr4:154626961-154753118 (+) GRCh38|
|Disease Associations||(2) Diseases Associated with Human LRAT|
Mice homozygous for disruptions in this gene exhibit retinol homeostasis abnormalities and are more susceptible to vitamin A deficiency or display impaired vision associated with abnormal retinol metabolism. Males have testicular hypoplasia/atrophy and reduced mature sperm counts.
|Process||1,2-diacyl-sn-glycero-3-phosphocholine metabolic process, embryo development, ...|
|Component||cytoplasm, endoplasmic reticulum, ...|
|Function||O-acyltransferase activity, phosphatidylcholine-retinol O-acyltransferase activity, ...|
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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