Sequence Detail

ID/Version

Q9JI60 (UniProt | EBI)

Last sequence update: 2000-10-01
Last annotation update: 2024-03-27

Sequence description from provider

RecName: Full=Lecithin retinol acyltransferase; EC=2.3.1.135 {ECO:0000305|PubMed:20628054};AltName: Full=Phosphatidylcholine--retinol O-acyltransferase;AltName: Full=Phosphatidylcholine-retinol-O-acyltransferase;

Provider

SWISS-PROT

Sequence

Polypeptide 231 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Lrat	lecithin-retinol acyltransferase (phosphatidylcholine-retinol-O-acyltransferase)	35	105	4	17

Sequence references in MGI

J:66429 Zolfaghari R, et al., Lecithin:retinol acyltransferase from mouse and rat liver. Cdna cloning and liver-specific regulation by dietary vitamin a and retinoic acid. J Lipid Res. 2000 Dec;41(12):2024-34
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:118552 Moise AR, et al., Topology and membrane association of lecithin: retinol acyltransferase. J Biol Chem. 2007 Jan 19;282(3):2081-90
J:219366 Zhang T, et al., Genetic deletion of S-opsin prevents rapid cone degeneration in a mouse model of Leber congenital amaurosis. Hum Mol Genet. 2015 Mar 15;24(6):1755-63
J:287029 Chelstowska S, et al., Impact of LCA-Associated E14L LRAT Mutation on Protein Stability and Retinoid Homeostasis. Biochemistry. 2017 Aug 29;56(34):4489-4499
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89