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Nlrp4c Gene Detail
Summary
  • Symbol
    Nlrp4c
  • Name
    NLR family, pyrin domain containing 4C
  • Synonyms
    Nalp4c, Nalp-alpha, Rnh2
  • Feature Type
    protein coding gene
  • IDs
    MGI:1890518
    NCBI Gene: 83564
  • Alliance
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr7:6048160-6108148 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
  • Genetic Map
    Chromosome 7, 3.50 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    228 from dbSNP Build 142
  • Strain Annotations
    15
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1890518
protein coding gene Chr7:6048160-6108149 (+)
129S1/SvImJ MGP_129S1SvImJ_G0031593
protein coding gene Chr7:3085927-3155995 (+)
A/J MGP_AJ_G0031567
protein coding gene Chr7:3015115-3082461 (+)
AKR/J MGP_AKRJ_G0031496
protein coding gene Chr7:3225813-3287613 (+)
BALB/cJ MGP_BALBcJ_G0031575
protein coding gene Chr7:3113441-3176550 (+)
C3H/HeJ MGP_C3HHeJ_G0031296
protein coding gene Chr7:3089932-3153203 (+)
C57BL/6NJ MGP_C57BL6NJ_G0032037
protein coding gene Chr7:3256584-3319987 (+)
CAROLI/EiJ no annotation
CAST/EiJ MGP_CASTEiJ_G0030659
protein coding gene Chr7:3009688-3039219 (+)
CBA/J MGP_CBAJ_G0031253
protein coding gene Chr7:3397706-3439330 (+)
DBA/2J MGP_DBA2J_G0031412
protein coding gene Chr7:3017967-3099932 (+)
FVB/NJ MGP_FVBNJ_G0031365
protein coding gene Chr7:3034183-3098593 (+)
LP/J MGP_LPJ_G0031497
protein coding gene Chr7:3164574-3255571 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0031404
protein coding gene Chr7:3351805-3444902 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0032066
protein coding gene Chr7:3016636-3097832 (+)
PWK/PhJ no annotation
SPRET/EiJ MGP_SPRETEiJ_G0030213
protein coding gene Chr7:2612933-2660162 (+)
WSB/EiJ no annotation



Homology
more
  • Human Ortholog
    NLRP4, NLR family pyrin domain containing 4
  • Vertebrate Orthologs
    8
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    NLRP4, NLR family pyrin domain containing 4
  • Synonyms
    CLR19.5, CT58, NALP4, PAN2, PYPAF4, RNH2
  • Links
    NCBI Gene ID: 147945
    neXtProt AC: NX_Q96MN2
    UniProt: Q96MN2

  • Chr Location
    19q13.43; chr19:55836540-55881855 (+)  GRCh38

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    5 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 83564 NCBI Gene Model | MGI Sequence Detail 59989 C57BL/6J ±  kb
transcript NM_031389 RefSeq | MGI Sequence Detail 3614 C57BL/6  
polypeptide Q3TKR3 UniProt | EBI | MGI Sequence Detail 982 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 9
    cDNA 7
    Primer pair 2

    Microarray probesets 2
References
more
  • Summaries
    All 27
    Developmental Gene Expression 5
    Gene Ontology 3
    Phenotypes 5
  • Earliest
    J:68614 Wang PJ, et al., An abundance of X-linked genes expressed in spermatogonia. Nat Genet. 2001 Apr;27(4):422-6
  • Latest
    J:221014 Madissoon E, et al., Differences in gene expression between mouse and human for dynamically regulated genes in early embryo. PLoS One. 2014;9(8):e102949

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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last database update
03/12/2024
MGI 6.23
The Jackson Laboratory