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Cdyl Gene Detail
Summary
  • Symbol
    Cdyl
  • Name
    chromodomain protein, Y chromosome-like
  • Feature Type
    protein coding gene
  • IDs
    MGI:1339956
    NCBI Gene: 12593
  • Alliance
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    Chr13:35659833-35874063 bp, + strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 13, 14.39 cM
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    1235 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1339956
protein coding gene Chr13:35659810-35874064 (+)
129S1/SvImJ MGP_129S1SvImJ_G0020458
protein coding gene Chr13:33840810-34060958 (+)
A/J MGP_AJ_G0020412
protein coding gene Chr13:32829049-33043197 (+)
AKR/J MGP_AKRJ_G0020390
protein coding gene Chr13:33622975-33853993 (+)
BALB/cJ MGP_BALBcJ_G0020408
protein coding gene Chr13:32890580-33106822 (+)
C3H/HeJ MGP_C3HHeJ_G0020207
protein coding gene Chr13:33505891-33727114 (+)
C57BL/6NJ MGP_C57BL6NJ_G0020841
protein coding gene Chr13:34980717-35212302 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0018428
protein coding gene Chr13:31057452-31265090 (+)
CAST/EiJ MGP_CASTEiJ_G0019722
protein coding gene Chr13:33204476-33441034 (+)
CBA/J MGP_CBAJ_G0020168
protein coding gene Chr13:36476230-36710584 (+)
DBA/2J MGP_DBA2J_G0020290
protein coding gene Chr13:32349019-32567256 (+)
FVB/NJ MGP_FVBNJ_G0020269
protein coding gene Chr13:31895531-32106859 (+)
LP/J MGP_LPJ_G0020365
protein coding gene Chr13:34074886-34301284 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0020299
protein coding gene Chr13:36643149-36878453 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0020884
protein coding gene Chr13:33234439-33455495 (+)
PWK/PhJ MGP_PWKPhJ_G0019477
protein coding gene Chr13:32457967-32677216 (+)
SPRET/EiJ MGP_SPRETEiJ_G0019308
protein coding gene Chr13:31940185-32172156 (+)
WSB/EiJ MGP_WSBEiJ_G0019784
protein coding gene Chr13:33596933-33821896 (+)



Homology
more
  • Human Ortholog
    CDYL, chromodomain Y like
  • Vertebrate Orthologs
    10
  • Human Ortholog
    CDYL, chromodomain Y like
    Orthology source: HomoloGene, HGNC
  • Synonyms
    CDYL1
  • Links
    NCBI Gene ID: 9425
    neXtProt AC: NX_Q9Y232
    UniProt: Q9Y232

  • Chr Location
    6p25.1; chr6:4706159-4955544 (+)  GRCh38.p7

  • HomoloGene
    Vertebrate Homology Class 3548
    1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;1 dog;1 chicken;1 zebrafish;1 frog, western clawed;1 macaque, rhesus
  • HCOP
    human homology predictions: CDYL
  • Gene Tree
Human Diseases
more
  • Diseases
    1 with Cdyl mouse models

Human Disease Mouse Models
      
IDs
View 1 model
Click on a disease name to see all genes associated with that disease.

  • Mutations/Alleles
    1 with disease annotations
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    4 phenotypes from 2 alleles in 2 genetic backgrounds
    14 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
immune system
integument
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
neoplasm
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
vision/eye

Click cells to view annotations.
  • All Mutations and Alleles
    67
  • Chemically induced (other)
    1
  • Endonuclease-mediated
    1
  • Gene trapped
    64
  • Targeted
    1
  • Genomic Mutations
    1 involving Cdyl
  • Incidental Mutations
    APF
  • Find Mice (IMSR)
Conditional homozygous knockout in the cerebral cortex affects neuronal migration and results in increased susceptibility to pharmacologically induced seizures.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000059288 Ensembl Gene Model | MGI Sequence Detail 214231 C57BL/6J ±  kb
transcript ENSMUST00000075220 Ensembl | MGI Sequence Detail 3470 Not Applicable  
polypeptide ENSMUSP00000074707 Ensembl | MGI Sequence Detail 593 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 16
    cDNA 15
    Primer pair 1

    Microarray probesets 6
Other
Accession IDs
less
MGI:2145214
References
more
  • Summaries
    All 50
    Developmental Gene Expression 3
    Diseases 1
    Gene Ontology 9
    Phenotypes 14
  • Earliest
    J:182573 Roderick TH, Producing and detecting paracentric chromosomal inversions in mice. Mutat Res. 1971 Jan;11(1):59-69
  • Latest
    J:277855 Parvanov ED, et al., PRDM9 interactions with other proteins provide a link between recombination hotspots and the chromosomal axis in meiosis. Mol Biol Cell. 2017 Feb 1;28(3):488-499

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
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last database update
10/08/2019
MGI 6.14
The Jackson Laboratory