Prkag2
Gene Detail

Symbol Name ID

Prkag2 protein kinase, AMP-activated, gamma 2 non-catalytic subunit MGI:1336153

Synonyms

2410051C13Rik

Feature Type

protein coding gene

Genetic Map

Chromosome 5

11.93 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)

Sequence Map

Chr5:24862744-25100642 bp, - strand From VEGA annotation of GRCm38   237899 bp   ±  kb flank VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser

Vertebrate homology

HomoloGene:90952  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 dog; 1 chicken; 1 zebrafish

Protein SuperFamily: AMP-activated protein kinase, gamma-type regulatory subunit
Gene Tree: Prkag2

Human homologs

Human Homolog		PRKAG2, protein kinase, AMP-activated, gamma 2 non-catalytic subunit
NCBI Gene ID		51422
neXtProt AC		NX_Q9UGJ0
Human Synonyms		AAKG, AAKG2, CMH6, H91620p, WPWS
Human Chr (Location)		7q36.1; chr7:151253200-151574316 (-)  GRCh37.p10
Disease Associations		(3) Diseases Associated with Human PRKAG2

Alleles and phenotypes

All alleles(10) : Targeted(2) Gene trapped(8)

Gene Ontology (GO) classifications

All GO classifications: (29 annotations)

Process	fatty acid biosynthetic process, fatty acid metabolic process, ...
Component	AMP-activated protein kinase complex
Function	ADP binding, AMP-activated protein kinase activity, ...

This is a GO Consortium Reference Genome Project gene.
External Resources: FuncBase

Expression

Literature Summary: (3 records)
Data Summary: Results (93)    Tissues (93)    Images (15)
Theiler Stages: 22

Assay Type	Results
RNA in situ	93

cDNA source data(11)
External Resources: Allen Institute   GEO   ArrayExpress

Molecular reagents

All nucleic(11) cDNA(11)
Microarray probesets(9)

Other database links

VEGA Gene Model	OTTMUSG00000023541 (Evidence)
Ensembl Gene Model	ENSMUSG00000028944 (Evidence)
Entrez Gene	108099 (Evidence)
DFCI	TC1575992, TC1588451, TC1595022, TC1625343
DoTS	DT.101725788, DT.40171296, DT.487668, DT.94258905
NIA Mouse Gene Index	U026007
Consensus CDS Project	CCDS19130.1, CCDS51437.1
International Mouse Knockout Project Status	Prkag2

Sequences

Length	Strain/Species
genomic	OTTMUSG00000023541	VEGA Gene Model | MGI Sequence Detail	237899	C57BL/6J
transcript	OTTMUST00000057395	VEGA | MGI Sequence Detail	3331	Not Applicable
polypeptide	OTTMUSP00000027683	VEGA | MGI Sequence Detail	566	Not Applicable

All sequences(74) RefSeq(6) UniProt(8)

Polymorphisms

SNPs(1782 from dbSNP Build 128)

Protein-related information

Resource	ID	Description
InterPro	IPR013785	Aldolase-type TIM barrel
InterPro	IPR000644	Cystathionine beta-synthase, core
Protein Ontology	PR:000013226	5'-AMP-activated protein kinase subunit gamma-2

References

(Earliest) J:54164 Turnley AM, et al., Cellular distribution and developmental expression of AMP-activated protein kinase isoforms in mouse central nervous system. J Neurochem. 1999 Apr;72(4):1707-16
(Latest) J:186631 Pinter K, et al., Embryonic expression of AMPK gamma subunits and the identification of a novel gamma2 transcript variant in adult heart. J Mol Cell Cardiol. 2012 Sep;53(3):342-9
All references(37)

Other accession IDs

MGI:1920950, MGI:2141005