About   Help   FAQ
Prkag2
Gene Detail
Symbol

Name
ID
Prkag2
protein kinase, AMP-activated, gamma 2 non-catalytic subunit
MGI:1336153
Synonyms
2410051C13Rik
Feature Type
protein coding gene
Genetic Map
Chromosome 5
11.93 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr5:24862744-25100642 bp, - strand
From VEGA annotation of GRCm38

  237899 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:136125  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

Protein SuperFamily: AMP-activated protein kinase, gamma-type regulatory subunit
Gene Tree: Prkag2

Human
homologs
Human Homolog PRKAG2, protein kinase, AMP-activated, gamma 2 non-catalytic subunit
NCBI Gene ID 51422
neXtProt AC  NX_Q9UGJ0
Human Synonyms  AAKG, AAKG2, CMH6, H91620p, WPWS
Human Chr (Location)  7q36.1; chr7:151556114-151877231 (-)  GRCh38
Disease Associations  (3) Diseases Associated with Human PRKAG2
Mutations,
alleles, and
phenotypes
All mutations/alleles(11) : Gene trapped(8) Radiation induced(1) Targeted(2)
Genomic Mutations involving Prkag2 (1)
Incidental mutations (data from Mutagenetix , APF )
Interactions
Prkag2 interacts with 261 markers (Mir1a-1, Mir1a-2, Mir1b, ...)
Gene Ontology
(GO)
classifications
Expression
Literature Summary: (3 records)
Data Summary: Results (168)    Tissues (119)    Images (15)    Tissue x Stage Matrix (view)
Assay TypeResults
Immunohistochemistry 13
RNA in situ 101
Western blot 5
RT-PCR 49
cDNA source data(13)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(23) cDNA(13) Primer pair(10)
Microarray probesets(9)
Other database
links
VEGA Gene ModelOTTMUSG00000023541 (Evidence)
Ensembl Gene ModelENSMUSG00000028944 (Evidence)
Entrez Gene108099 (Evidence)
DFCITC1588451, TC1575992, TC1625343, TC1595022
DoTSDT.101725788, DT.94258905, DT.487668, DT.40171296
NIA Mouse Gene IndexU026007
Consensus CDS ProjectCCDS19130.1, CCDS51437.1
International Mouse Knockout Project StatusPrkag2
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000023541 VEGA Gene Model | MGI Sequence Detail 237899 C57BL/6J ±  kb
transcript OTTMUST00000057395 VEGA | MGI Sequence Detail 3331 Not Applicable 
polypeptide OTTMUSP00000027683 VEGA | MGI Sequence Detail 566 Not Applicable 

For the selected sequences
All sequences(90) RefSeq(15) UniProt(15)
Polymorphisms
SNPs within 2kb(2493 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR000644 Cystathionine beta-synthase, core
Protein Ontology PR:000013226 5'-AMP-activated protein kinase subunit gamma-2
References
(Earliest) J:54164 Turnley AM, et al., Cellular distribution and developmental expression of AMP-activated protein kinase isoforms in mouse central nervous system. J Neurochem. 1999 Apr;72(4):1707-16
(Latest) J:186631 Pinter K, et al., Embryonic expression of AMPK gamma subunits and the identification of a novel gamma2 transcript variant in adult heart. J Mol Cell Cardiol. 2012 Sep;53(3):342-9
All references(36)
Other
accession IDs
MGI:1920950, MGI:2141005

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
12/09/2014
MGI 5.20
The Jackson Laboratory