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Prkag2
Gene Detail
Symbol

Name
ID
Prkag2
protein kinase, AMP-activated, gamma 2 non-catalytic subunit
MGI:1336153
Synonyms
2410051C13Rik
Feature Type
protein coding gene
Genetic Map
Chromosome 5
11.93 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr5:24862744-25100642 bp, - strand
From VEGA annotation of GRCm38

  237899 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:136125  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

HCOP human homology predictions: PRKAG2
Protein SuperFamily: AMP-activated protein kinase, gamma-type regulatory subunit
Gene Tree: Prkag2

Human
homologs
PRKAG2, protein kinase, AMP-activated, gamma 2 non-catalytic subunit
Orthology source: HomoloGene, HGNC

IDs:
NCBI Gene ID: 51422
neXtProt AC: NX_Q9UGJ0

Human Synonyms: AAKG, AAKG2, CMH6, H91620p, WPWS

Human Chr (Location): 7q36.1; chr7:151556114-151877231 (-)  GRCh38.p2

Disease Associations: (3) Diseases Associated with Human PRKAG2

Mutations,
alleles, and
phenotypes
All mutations/alleles(14) : Gene trapped(8) Radiation induced(1) Targeted(2) Transgenic(3)
Genomic Mutations involving Prkag2 (1)
Incidental mutations (data from Mutagenetix , APF )
Mutations Annotated to Human Diseases (3)   
Interactions
Prkag2 interacts with 260 markers (Mir1a-1, Mir1a-2, Mir1b, ...)
Gene Ontology
(GO)
classifications
Expression
Literature Summary: (3 records)
Data Summary: Results (168)    Tissues (119)    Images (15)    Tissue x Stage Matrix (view)
Assay TypeResults
Immunohistochemistry 13
RNA in situ 101
Western blot 5
RT-PCR 49
cDNA source data(13)
Other mouse links: Allen Institute   GEO   Expression Atlas
Other vertebrate links: GEISHA PRKAG2 ; Xenbase prkag2    NEW 
Molecular
reagents
All nucleic(23) cDNA(13) Primer pair(10)
Microarray probesets(9)
Other database
links
VEGA Gene Model OTTMUSG00000023541 (Evidence)
Ensembl Gene Model ENSMUSG00000028944 (Evidence)
Entrez Gene 108099 (Evidence)
DFCI TC1625343, TC1595022, TC1575992, TC1588451
DoTS DT.101725788, DT.40171296, DT.487668, DT.94258905
NIA Mouse Gene Index U026007
Consensus CDS Project CCDS19130.1, CCDS51437.1
International Mouse Phenotyping Consortium Status Prkag2
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000023541 VEGA Gene Model | MGI Sequence Detail 237899 C57BL/6J ±  kb
transcript OTTMUST00000057395 VEGA | MGI Sequence Detail 3331 Not Applicable 
polypeptide OTTMUSP00000027683 VEGA | MGI Sequence Detail 566 Not Applicable 

For the selected sequences
All sequences(86) RefSeq(18) UniProt(8)
Polymorphisms
SNPs within 2kb(2493 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR000644 Cystathionine beta-synthase, core
Protein Ontology PR:000013226 5'-AMP-activated protein kinase subunit gamma-2
References
(Earliest) J:54164 Turnley AM, et al., Cellular distribution and developmental expression of AMP-activated protein kinase isoforms in mouse central nervous system. J Neurochem. 1999 Apr;72(4):1707-16
(Latest) J:186631 Pinter K, et al., Embryonic expression of AMPK gamma subunits and the identification of a novel gamma2 transcript variant in adult heart. J Mol Cell Cardiol. 2012 Sep;53(3):342-9
All references(35)
Other
accession IDs
MGI:1920950, MGI:2141005

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
05/20/2015
MGI 5.22
The Jackson Laboratory