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Edil3
Gene Detail
 Symbol
Name
ID
Edil3
EGF-like repeats and discoidin I-like domains 3
MGI:1329025
Synonyms Del1, Del-1, developmental endothelial locus-1
Feature Type protein coding gene
Genetic Map
Chromosome 13
45.30 cM, cytoband C3
Detailed Genetic Map ± 1 cM


Mapping data(3)
Sequence Map
Chr13:88821472-89323223 bp, + strand
From VEGA annotation of GRCm38

  501752 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:21166  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 zebrafish

Protein SuperFamily: lactadherin-like protein
Gene Tree: Edil3

Human
homologs
Human Homolog EDIL3, EGF-like repeats and discoidin I-like domains 3
NCBI Gene ID 10085
neXtProt AC  NX_O43854
Human Synonyms  DEL1
Human Chr (Location)  5q14; chr5:83940595-84384867 (-)  GRCh38
Alleles
and
phenotypes
All alleles(4) : Targeted(4)
Incidental mutations (data from Mutagenetix , APF )
 
Mice homozygous for a null mutation are viable and fertile with no noticeable fur phenotype.
 
Gene Ontology
(GO)
classifications
All GO classifications: (8 annotations)
Process cell adhesion, multicellular organismal development, ...
Component extracellular region, extracellular vesicular exosome
Function calcium ion binding, metal ion binding
External Resources: FuncBase
Expression
Literature Summary: (7 records)
Data Summary: Results (20)    Tissues (11)    Images (11)
Theiler Stages: 15, 19, 20, 21, 22, 24, 25
Assay TypeResults
RNA in situ 12
RT-PCR 8
cDNA source data(15)
External Resources: Allen Institute   GEO   ArrayExpress
Molecular
reagents
All nucleic(26) Genomic(1) cDNA(21) Primer pair(3) Other(1)
Microarray probesets(10)
Other database
links
VEGA Gene ModelOTTMUSG00000027759 (Evidence)
Ensembl Gene ModelENSMUSG00000034488 (Evidence)
Entrez Gene13612 (Evidence)
DFCITC1581996, TC1592204, TC1598798, TC1606701, TC1627255, TC1640086, TC1727069
DoTSDT.110977052, DT.55111976, DT.55123024, DT.55222259, DT.91335447, DT.91481851
NIA Mouse Gene IndexU015083
Consensus CDS ProjectCCDS26669.1, CCDS26670.1
International Mouse Knockout Project StatusEdil3
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000027759 VEGA Gene Model | MGI Sequence Detail 501752 C57BL/6J ±  kb
transcript OTTMUST00000068691 VEGA | MGI Sequence Detail 5317 Not Applicable 
polypeptide OTTMUSP00000034781 VEGA | MGI Sequence Detail 480 Not Applicable 

For the selected sequences
All sequences(65) RefSeq(4) UniProt(3)
Polymorphisms SNPs within 2kb(4215 from dbSNP Build 137)    SNPs within 2kb including multiple locations(4217)
Protein-related
information
ResourceIDDescription
InterPro IPR000421 Coagulation factor 5/8 C-terminal type domain
InterPro IPR001881 EGF-like calcium-binding
InterPro IPR018097 EGF-like calcium-binding, conserved site
InterPro IPR013032 EGF-like, conserved site
InterPro IPR000152 EGF-type aspartate/asparagine hydroxylation site
InterPro IPR000742 Epidermal growth factor-like domain
InterPro IPR008979 Galactose-binding domain-like
Protein Ontology PR:000006896 EGF-like repeat and discoidin I-like domain-containing protein 3
References (Earliest) J:45380 Hidai C, et al., Cloning and characterization of developmental endothelial locus-1: an embryonic endothelial cell protein that binds the alphavbeta3 integrin receptor. Genes Dev. 1998 Jan 1;12(1):21-33
(Latest) J:196404 Kanczkowski W, et al., Role of the endothelial-derived endogenous anti-inflammatory factor Del-1 in inflammation-mediated adrenal gland dysfunction. Endocrinology. 2013 Mar;154(3):1181-9
All references(40)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
07/15/2014
MGI 5.18
The Jackson Laboratory