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Rtf1
Gene Detail
 Symbol
Name
ID
Rtf1
Rtf1, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae)
MGI:1309480
Synonyms 2900005O08Rik, 6530416A09Rik, Gtl7
Feature Type protein coding gene
Genetic Map
Chromosome 2
59.97 cM, cytoband E5
Detailed Genetic Map ± 1 cM


Mapping data(4)
Sequence Map
Chr2:119675068-119735407 bp, + strand
From VEGA annotation of GRCm38

  60340 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:133868  Vertebrate Homology Class
1 human; 1 mouse; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

Protein SuperFamily: RNA polymerase-associated protein Rtf1
Gene Tree: Rtf1

Human
homologs
Human Homolog RTF1, Rtf1, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae)
NCBI Gene ID 23168
neXtProt AC  NX_Q92541
Human Synonyms  GTL7, KIAA0252
Human Chr (Location)  15q15.1; chr15:41417104-41483563 (+)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(37) : Gene trapped(35) Targeted(2)
Incidental mutations (data from Mutagenetix , APF )
Interactions
Rtf1 interacts with 364 markers (Mir7-1, Mir7-2, Mir7b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (21 annotations)
Process DNA-templated transcription, initiation, endodermal cell fate commitment, ...
Component Cdc73/Paf1 complex, nucleolus, ...
Function DNA binding, poly(A) RNA binding, ...
External Resources: FuncBase
Expression
Literature Summary: (2 records)
Data Summary: Results (13)    Tissues (9)    Images (3)
Theiler Stages: 24, 26, 27, 28
Assay TypeResults
RNA in situ 13
cDNA source data(100)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(101) cDNA(101)
Microarray probesets(4)
Other database
links
VEGA Gene ModelOTTMUSG00000016508 (Evidence)
Ensembl Gene ModelENSMUSG00000027304 (Evidence)
Entrez Gene76246 (Evidence)
UniGene33437
DFCITC1601093, TC1611302, TC1617275, TC1620370
DoTSDT.101385738, DT.103583627, DT.491322
NIA Mouse Gene IndexU002321
Consensus CDS ProjectCCDS50673.1
International Mouse Knockout Project StatusRtf1
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000016508 VEGA Gene Model | MGI Sequence Detail 60340 C57BL/6J ±  kb
transcript OTTMUST00000039888 VEGA | MGI Sequence Detail 4664 Not Applicable 
polypeptide OTTMUSP00000017790 VEGA | MGI Sequence Detail 715 Not Applicable 

For the selected sequences
All sequences(57) RefSeq(6) UniProt(6)
Polymorphisms SNPs within 2kb(479 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR004343 Plus-3
InterPro IPR018144 Plus-3 domain, subgroup
Protein Ontology PR:000014341 RNA polymerase-associated protein RTF1
References (Earliest) J:50092 Tate P, et al., Capturing novel mouse genes encoding chromosomal and other nuclear proteins. J Cell Sci. 1998 Sep;111(Pt 17):2575-85
(Latest) J:203796 Zhang K, et al., CTR9/PAF1c regulates molecular lineage identity, histone H3K36 trimethylation and genomic imprinting during preimplantation development. Dev Biol. 2013 Nov 1;383(1):15-27
All references(42)
Other
accession IDs
MGI:1923496, MGI:1925759, MGI:2139096, MGI:2139215, MGI:2139393

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
09/16/2014
MGI 5.19
The Jackson Laboratory