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Myt1l Gene Detail
Summary
  • Symbol
    Myt1l
  • Name
    myelin transcription factor 1-like
  • Synonyms
    2900046C06Rik, 2900093J19Rik, C630034G21Rik, mKIAA1106, Nztf1, Pmng1, Png-1
  • Feature Type
    protein coding gene
  • IDs
    MGI:1100511
    NCBI Gene: 17933
  • Alliance
  • Transcription Start Sites
    11 TSS
Location &
Maps
more
  • Sequence Map
    Chr12:29528384-29923213 bp, + strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 12, 11.86 cM
  • Mapping Data
    4 experiments
Strain
Comparison
more
  • SNPs within 2kb
    4261 from dbSNP Build 142
  • Strain Annotations
    18
  • RFLP
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1100511
protein coding gene Chr12:29528328-29923216 (.)
129S1/SvImJ MGP_129S1SvImJ_G0019648
protein coding gene Chr12:27397749-27811854 (+)
A/J MGP_AJ_G0019615
protein coding gene Chr12:26636534-27043741 (+)
AKR/J MGP_AKRJ_G0019586
protein coding gene Chr12:27531567-27935725 (+)
BALB/cJ MGP_BALBcJ_G0019592
protein coding gene Chr12:26892383-27296587 (+)
C3H/HeJ MGP_C3HHeJ_G0019396
protein coding gene Chr12:27378602-27783897 (+)
C57BL/6NJ MGP_C57BL6NJ_G0020039
protein coding gene Chr12:28281269-28689784 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0017664
protein coding gene Chr12:25991288-26384321 (+)
CAST/EiJ MGP_CASTEiJ_G0018951
protein coding gene Chr12:22361090-22776238 (+)
CBA/J MGP_CBAJ_G0019367
protein coding gene Chr12:29252480-29659433 (+)
DBA/2J MGP_DBA2J_G0019481
protein coding gene Chr12:26488324-26887674 (+)
FVB/NJ MGP_FVBNJ_G0019472
protein coding gene Chr12:26299752-26701784 (+)
LP/J MGP_LPJ_G0019551
protein coding gene Chr12:27486488-27902250 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0019507
protein coding gene Chr12:28846218-29257042 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0020079
protein coding gene Chr12:27051360-27459566 (+)
PWK/PhJ MGP_PWKPhJ_G0018718
protein coding gene Chr12:21210270-21611269 (+)
SPRET/EiJ MGP_SPRETEiJ_G0018506
protein coding gene Chr12:21645739-22048278 (+)
WSB/EiJ MGP_WSBEiJ_G0019002
protein coding gene Chr12:27264942-27670380 (+)



Homology
more
  • Human Ortholog
    MYT1L, myelin transcription factor 1 like
  • Vertebrate Orthologs
    10
  • Human Ortholog
    MYT1L, myelin transcription factor 1 like
    Orthology source: HomoloGene, HGNC
  • Synonyms
    MRD39, myT1-L, NZF1, ZC2H2C2, ZC2HC4B
  • Links
    NCBI Gene ID: 23040
    neXtProt AC: NX_Q9UL68
    UniProt: Q9UL68

  • Chr Location
    2p25.3; chr2:1789113-2331388 (-)  GRCh38.p7

  • HomoloGene
    Vertebrate Homology Class 7435
    1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;1 dog;1 chicken;1 zebrafish;1 frog, western clawed;1 macaque, rhesus
  • HCOP
    human homology predictions: MYT1L
  • Gene Tree
Human Diseases
more
  • Diseases
    1 with human MYT1L associations

Human Disease Mouse Models
      
IDs
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    3 phenotype references
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000061911 Ensembl Gene Model | MGI Sequence Detail 394830 C57BL/6J ±  kb
transcript ENSMUST00000049784 Ensembl | MGI Sequence Detail 7202 Not Applicable  
polypeptide ENSMUSP00000058264 Ensembl | MGI Sequence Detail 1187 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 33
    cDNA 29
    Primer pair 4

    Microarray probesets 8
Other
Accession IDs
less
MGD-MRK-36441, MGI:107864, MGI:1920146, MGI:1920316, MGI:2443117, MGI:891972
References
more
  • Summaries
    All 51
    Developmental Gene Expression 17
    Gene Ontology 9
    Phenotypes 3
  • Earliest
    J:39021 Jiang Y, et al., A novel family of Cys-Cys, His-Cys zinc finger transcription factors expressed in developing nervous system and pituitary gland. J Biol Chem. 1996 May 3;271(18):10723-30
  • Latest
    J:257654 Memic F, et al., Transcription and Signaling Regulators in Developing Neuronal Subtypes of Mouse and Human Enteric Nervous System. Gastroenterology. 2018 Feb;154(3):624-636

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/06/2018
MGI 6.13
The Jackson Laboratory