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Myt1l Gene Detail
Summary
  • Symbol
    Myt1l
  • Name
    myelin transcription factor 1-like
  • Synonyms
    2900046C06Rik, 2900093J19Rik, C630034G21Rik, mKIAA1106, Nztf1, Pmng1, Png-1
  • Feature Type
    protein coding gene
  • IDs
    MGI:1100511
    NCBI Gene: 17933
  • Alliance
Location & Maps
more
  • Sequence Map
    Chr12:29528384-29923213 bp, + strand
  • From Ensembl annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      394830 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 12, 11.86 cM
  • Mapping Data
    4 experiments
Homology
more
  • Human Ortholog
    MYT1L, myelin transcription factor 1 like
  • Vertebrate Orthologs
    10
  • Human Ortholog
    MYT1L, myelin transcription factor 1 like
    Orthology source: HomoloGene, HGNC
  • Synonyms
    MRD39, myT1-L, NZF1, ZC2H2C2, ZC2HC4B
  • Links
    NCBI Gene ID: 23040
    neXtProt AC: NX_Q9UL68
    UniProt: Q9UL68

  • Chr Location
    2p25.3; chr2:1789113-2331388 (-)  GRCh38.p7

  • HomoloGene
    Vertebrate Homology Class 7435
    1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;1 dog;1 chicken;1 zebrafish;1 frog, western clawed;1 macaque, rhesus
  • HCOP
    human homology predictions: MYT1L
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    3 phenotype references
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000061911 Ensembl Gene Model | MGI Sequence Detail 394830 C57BL/6J ±  kb
transcript ENSMUST00000049784 Ensembl | MGI Sequence Detail 7202 Not Applicable  
polypeptide ENSMUSP00000058264 Ensembl | MGI Sequence Detail 1187 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    4261 from dbSNP Build 142
  • RFLP
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 30
    cDNA 26
    Primer pair 4

    Microarray probesets 8
Other
Accession IDs
less
MGD-MRK-36441, MGI:107864, MGI:1920146, MGI:1920316, MGI:2443117, MGI:891972
References
more
  • Summaries
    All 46
    Developmental Gene Expression 15
    Gene Ontology 7
    Phenotypes 3
  • Earliest
    J:39021 Jiang Y, et al., A novel family of Cys-Cys, His-Cys zinc finger transcription factors expressed in developing nervous system and pituitary gland. J Biol Chem. 1996 May 3;271(18):10723-30
  • Latest
    J:240999 Mall M, et al., Myt1l safeguards neuronal identity by actively repressing many non-neuronal fates. Nature. 2017 Apr 13;544(7649):245-249

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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Funding Information
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last database update
10/10/2017
MGI 6.10
The Jackson Laboratory