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Emp2 Gene Detail
Summary
  • Symbol
    Emp2
  • Name
    epithelial membrane protein 2
  • Synonyms
    Xmp
  • Feature Type
    protein coding gene
  • IDs
    MGI:1098726
    NCBI Gene: 13731
  • Gene Overview
    MyGene.info: EMP2
Location & Maps
more
  • Sequence Map
    Chr16:10281749-10313968 bp, - strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      32220 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 16, 5.54 cM
  • Mapping Data
    3 experiments
Homology
more
  • Human Ortholog
    EMP2, epithelial membrane protein 2
  • Vertebrate Orthologs
    10
  • Human Ortholog
    EMP2, epithelial membrane protein 2
    Orthology source: HGNC, HomoloGene
  • Synonyms
    XMP
  • Links
    NCBI Gene ID: 2013
    neXtProt AC: NX_P54851

  • Chr Location
    16p13.2; chr16:10528422-10580682 (-)  GRCh38.p2

Human Diseases
more
  • Diseases
    1 with human EMP2 associations

Human Disease Mouse Models
       Nephrotic Syndrome, Type 10; NPHS10   OMIM: 615861
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    3 phenotype references
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000035738 VEGA Gene Model | MGI Sequence Detail 32220 C57BL/6J ±  kb
transcript OTTMUST00000091380 VEGA | MGI Sequence Detail 3440 Not Applicable  
polypeptide OTTMUSP00000050334 VEGA | MGI Sequence Detail 172 Not Applicable  
For the selected sequence
Polymorphisms
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  • SNPs within 2kb
    107 from dbSNP Build 142
  • RFLP
Protein
Information
less
  • UniProt
    5 Sequences
  • Protein Ontology
    PR:000007063 epithelial membrane protein 2
  • InterPro Domains
    IPR003933 Epithelial membrane protein 2
    IPR004032 PMP-22/EMP/MP20
    IPR004031 PMP-22/EMP/MP20/Claudin superfamily
Molecular
Reagents
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  • All nucleic 84
    Genomic 1
    cDNA 83

    Microarray probesets 7
References
more
  • Summaries
    All 33
    Developmental Gene Expression 3
    Gene Ontology 10
    Phenotypes 3
  • Earliest
    J:37229 Ben-Porath I, et al., Characterization of a tumor-associated gene, a member of a novel family of genes encoding membrane glycoproteins. Gene. 1996 Dec 12;183(1-2):69-75
  • Latest
    J:190524 Shalom-Barak T, et al., Placental PPARgamma regulates spatiotemporally diverse genes and a unique metabolic network. Dev Biol. 2012 Dec 1;372(1):143-55

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
06/15/2016
MGI 6.04
The Jackson Laboratory