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Taf1b Gene Detail
Summary
  • Symbol
    Taf1b
  • Name
    TATA-box binding protein associated factor, RNA polymerase I, B
  • Synonyms
    4930408G01Rik, A230108M10Rik, mTAFI68, p63
  • Feature Type
    protein coding gene
  • IDs
    MGI:109577
    NCBI Gene: 21340
  • Gene Overview
    MyGene.info: TAF1B
Location & Maps
more
  • Sequence Map
    Chr12:24498581-24558571 bp, + strand
  • From NCBI annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      59991 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 12, 8.49 cM, cytoband A3
  • Mapping Data
    3 experiments
Homology
more
  • Human Ortholog
    TAF1B, TATA-box binding protein associated factor, RNA polymerase I subunit B
  • Vertebrate Orthologs
    10
  • Human Ortholog
    TAF1B, TATA-box binding protein associated factor, RNA polymerase I subunit B
    Orthology source: HGNC, HomoloGene
  • Synonyms
    MGC:9349, RAF1B, RAFI63, SL1, TAFI63
  • Links
    NCBI Gene ID: 9014
    neXtProt AC: NX_Q53T94

  • Chr Location
    2p25; chr2:9843442-9934416 (+)  GRCh38.p2

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    4 phenotype references
  • All Mutations and Alleles
    14
  • Gene trapped
    12
  • Targeted
    2
  • Incidental Mutations
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 21340 NCBI Gene Model | MGI Sequence Detail 59991 C57BL/6J ±  kb
transcript NM_020614 RefSeq | MGI Sequence Detail 2019 C57BL/6  
polypeptide P97358 UniProt | EBI | MGI Sequence Detail 586 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    404 from dbSNP Build 142
Protein
Information
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  • UniProt
    1 Sequence
  • Protein Ontology
    PR:000016021 TATA box-binding protein-associated factor RNA polymerase I subunit B
  • InterPro Domains
    IPR033599 RNA polymerase I transcription initiation factor TAF1B/Rrn7
    IPR021752 Transcription initiation factor Rrn7, Zinc-finger
Molecular
Reagents
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  • All nucleic 16
    cDNA 16

    Microarray probesets 3
Other
Accession IDs
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MGD-MRK-39576, MGI:1922100, MGI:1925679
References
more
  • Summaries
    All 33
    Developmental Gene Expression 2
    Gene Ontology 6
    Phenotypes 4
  • Earliest
    J:35896 Almendral JM, et al., Expression, cloning and cDNA sequence of a fibroblast serum-regulated gene encoding a putative actin-associated protein (p27). Exp Cell Res. 1989 Apr;181(2):518-30
  • Latest
    J:210838 Adolphe C, et al., Patched 1 and patched 2 redundancy has a key role in regulating epidermal differentiation. J Invest Dermatol. 2014 Jul;134(7):1981-90

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
08/17/2016
MGI 6.05
The Jackson Laboratory