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Tubb4a Gene Detail
Summary
  • Symbol
    Tubb4a
  • Name
    tubulin, beta 4A class IVA
  • Synonyms
    Tubb, Tubb4
  • Feature Type
    protein coding gene
  • IDs
    MGI:107848
    NCBI Gene: 22153
  • Gene Overview
    MyGene.info: TUBB4A
Location & Maps
more
  • Sequence Map
    Chr17:57080066-57087782 bp, - strand
  • From NCBI annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      7717 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 17, 29.66 cM
  • Mapping Data
    3 experiments
Homology
more
  • Human Ortholog
    TUBB4A, tubulin beta 4A class IVa
  • Vertebrate Orthologs
    9
  • Human Ortholog
    TUBB4A, tubulin beta 4A class IVa
    Orthology source: HGNC, HomoloGene
  • Synonyms
    beta-5, DYT4, TUBB4
  • Links
    NCBI Gene ID: 10382
    neXtProt AC: NX_P04350

  • Chr Location
    19p13.3; chr19:6494319-6502848 (-)  GRCh38.p2

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    4 phenotype references
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 22153 NCBI Gene Model | MGI Sequence Detail 7717 C57BL/6J ±  kb
transcript NM_009451 RefSeq | MGI Sequence Detail 2246 C57BL/6  
polypeptide Q9D6F9 UniProt | EBI | MGI Sequence Detail 444 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    55 from dbSNP Build 142
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 68
    Genomic 1
    cDNA 62
    Primer pair 4
    Other 1

    Microarray probesets 3
Other
Accession IDs
less
MGD-MRK-15302, MGD-MRK-36425, MGI:2146828, MGI:98870
References
more
  • Summaries
    All 87
    Developmental Gene Expression 49
    Gene Ontology 9
    Phenotypes 4
  • Earliest
    J:31028 Cleveland DW, et al., Number and evolutionary conservation of alpha- and beta-tubulin and cytoplasmic beta- and gamma-actin genes using specific cloned cDNA probes. Cell. 1980 May;20(1):95-105
  • Latest
    J:233746 Wang X, et al., Expression of histone deacetylase 3 instructs alveolar type I cell differentiation by regulating a Wnt signaling niche in the lung. Dev Biol. 2016 Jun 15;414(2):161-9

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
08/17/2016
MGI 6.05
The Jackson Laboratory