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Polr2m Gene Detail
Summary
  • Symbol
    Polr2m
  • Name
    polymerase (RNA) II (DNA directed) polypeptide M
  • Synonyms
    D9Wsu138e, Grinl1a
  • Feature Type
    protein coding gene
  • IDs
    MGI:107282
    NCBI Gene: 28015
  • Gene Overview
    MyGene.info: POLR2M
  • Alliance
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    Chr9:71478437-71485935 bp, - strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 9, 39.85 cM
  • Mapping Data
    5 experiments
Strain
Comparison
more
  • SNPs within 2kb
    44 from dbSNP Build 142
  • Strain Annotations
    18
  • PCR
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_107282
protein coding gene Chr9:71478437-71485983 (-)
129S1/SvImJ MGP_129S1SvImJ_G0035008
protein coding gene Chr9:71597091-71604538 (-)
A/J MGP_AJ_G0034989
protein coding gene Chr9:69085296-69092741 (-)
AKR/J MGP_AKRJ_G0034918
protein coding gene Chr9:70748139-70755586 (-)
BALB/cJ MGP_BALBcJ_G0034981
protein coding gene Chr9:68807154-68814599 (-)
C3H/HeJ MGP_C3HHeJ_G0034690
protein coding gene Chr9:71257242-71264687 (-)
C57BL/6NJ MGP_C57BL6NJ_G0035500
protein coding gene Chr9:73490457-73497949 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0032411
protein coding gene Chr9:68608083-68615739 (-)
CAST/EiJ MGP_CASTEiJ_G0034012
protein coding gene Chr9:71534247-71541754 (-)
CBA/J MGP_CBAJ_G0034663
protein coding gene Chr9:76037295-76044740 (-)
DBA/2J MGP_DBA2J_G0034822
protein coding gene Chr9:68818954-68826399 (-)
FVB/NJ MGP_FVBNJ_G0034764
protein coding gene Chr9:68140348-68147845 (-)
LP/J MGP_LPJ_G0034903
protein coding gene Chr9:71810859-71818306 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0034805
protein coding gene Chr9:77096625-77104070 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0035522
protein coding gene Chr9:70883963-70891408 (-)
PWK/PhJ MGP_PWKPhJ_G0033716
protein coding gene Chr9:69073211-69080842 (-)
SPRET/EiJ MGP_SPRETEiJ_G0033549
protein coding gene Chr9:71195943-71206061 (-)
WSB/EiJ MGP_WSBEiJ_G0034125
protein coding gene Chr9:70820996-70827509 (-)



Homology
more
  • Human Ortholog
    POLR2M, RNA polymerase II subunit M
  • Vertebrate Orthologs
    8
  • Human Ortholog
    POLR2M, RNA polymerase II subunit M
    Orthology source: HomoloGene, HGNC
  • Synonyms
    GCOM1, Gdown, Gdown1, GRINL1A
  • Links
    NCBI Gene ID: 81488
    neXtProt AC: NX_P0CAP1, NX_P0CAP2, NX_Q6EEV4
    UniProt: P0CAP2, Q6EEV4

  • Chr Location
    15q21.3; chr15:57706521-57717557 (+)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    5 phenotype references
  • All Mutations and Alleles
    5
  • Chemically induced (other)
    1
  • Gene trapped
    2
  • Targeted
    2
  • Genomic Mutations
    1 involving Polr2m
  • Find Mice (IMSR)
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000032199 Ensembl Gene Model | MGI Sequence Detail 7499 C57BL/6J ±  kb
transcript ENSMUST00000034720 Ensembl | MGI Sequence Detail 2200 Not Applicable  
polypeptide ENSMUSP00000034720 Ensembl | MGI Sequence Detail 366 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 332
    cDNA 330
    Primer pair 2

    Microarray probesets 2
Other
Accession IDs
less
MGD-MRK-35747, MGI:2142907, MGI:2142926, MGI:2143009, MGI:2143327
References
more
  • Summaries
    All 35
    Developmental Gene Expression 3
    Gene Ontology 5
    Phenotypes 5
  • Earliest
    J:50869 Ko MSH, et al., Genome-wide mapping of unselected transcripts from extraembryonic tissue of 7.5-day mouse embryos reveals enrichment in the t-complex and under-representation on the X chromosome. Hum Mol Genet. 1998 Nov;7(12):1967-78
  • Latest
    J:215487 Thompson CL, et al., A high-resolution spatiotemporal atlas of gene expression of the developing mouse brain. Neuron. 2014 Jul 16;83(2):309-23

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/13/2018
MGI 6.13
The Jackson Laboratory