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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID
Polr2m
polymerase (RNA) II (DNA directed) polypeptide M
MGI:107282
5 phenotypes from multigenic genotypes
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Allelic Composition
Genetic Background
Annotated Term Reference
Albtm1(cre/ERT2)Mtz/Alb+
Polr2mtm1.1Rgr/Polr2mtm1.1Rgr
Trp53tm1Tyj/Trp53tm1Tyj
involves: 129S2/SvPas * C57BL/6
increased hepatocyte karyomegaly J:291184
increased hepatocyte proliferation J:291184
Polr2mtm1.1Rgr/Polr2mtm1.1Rgr
Speer6-ps1Tg(Alb-cre)21Mgn/Speer6-ps1+
Trp53tm1Tyj/Trp53tm1Tyj
involves: 129S2/SvPas * C57BL/6 * DBA
abnormal hepatocyte morphology J:291184
abnormal liver morphology J:291184
increased hepatocyte apoptosis J:291184
increased hepatocyte proliferation J:291184

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory