Polr2m Phenotype Annotations

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Polr2m
polymerase (RNA) II (DNA directed) polypeptide M
MGI:107282

7 phenotypes from 2 alleles in 2 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Polr2m^tm1.1Rgr/Polr2m^tm1.1Rgr Speer6-ps1^{Tg(Alb-cre)21Mgn}/Speer6-ps1⁺ involves: C57BL/6 * DBA	abnormal hepatocyte physiology	J:291184
	decreased circulating triglyceride level	J:291184
	increased circulating alkaline phosphatase level	J:291184
	increased hepatocyte karyomegaly	J:291184
	normal liver/biliary system phenotype	J:291184
Polr2m^tm1.2Rgr/Polr2m^tm1.2Rgr involves: C57BL/6 * FVB/N	embryonic lethality before implantation, incomplete penetrance	J:291184
Polr2m^tm1.2Rgr/Polr2m^tm1.2Rgr involves: C57BL/6 * FVB/N	embryonic lethality during organogenesis, complete penetrance	J:291184

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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