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Myo5b
Gene Detail
 Symbol
Name
ID
Myo5b
myosin VB
MGI:106598
Feature Type protein coding gene
Genetic Map
Chromosome 18
50.70 cM
Detailed Genetic Map ± 1 cM


Mapping data(6)
Sequence Map
Chr18:74440936-74771493 bp, + strand
From VEGA annotation of GRCm38

  330558 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:49481  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 2 zebrafish

Gene Tree: Myo5b

Human
homologs
Human Homolog MYO5B, myosin VB
NCBI Gene ID 4645
neXtProt AC  NX_Q9ULV0
Human Chr (Location)  18q21; chr18:49822786-50195081 (-)  GRCh38
Disease Associations  (1) Diseases Associated with Human MYO5B
Alleles
and
phenotypes
All alleles(5) : Gene trapped(2) Targeted(3)
Incidental mutations (data from Mutagenetix , APF )
Gene Ontology
(GO)
classifications
All GO classifications: (23 annotations)
Process metabolic process, protein transport, ...
Component dendritic spine, extracellular vesicular exosome, ...
Function actin binding, ATP binding, ...
External Resources: FuncBase
Expression
Literature Summary: (4 records)
Data Summary: Results (102)    Tissues (54)    Images (20)
Theiler Stages: 23, 26, 27
Assay TypeResults
RNA in situ 102
cDNA source data(47)
External Resources: Allen Institute   GEO   ArrayExpress
Molecular
reagents
All nucleic(53) cDNA(52) Primer pair(1)
Microarray probesets(7)
Other database
links
VEGA Gene ModelOTTMUSG00000029560 (Evidence)
Ensembl Gene ModelENSMUSG00000025885 (Evidence)
Entrez Gene17919 (Evidence)
UniGene260098
DFCITC1583892, TC1589259, TC1597431, TC1611756, TC1625430, TC1674612, TC1699038
DoTSDT.101367827, DT.110756878, DT.110756887, DT.40175166, DT.526952, DT.94391489, DT.97394580
NIA Mouse Gene IndexU018896
Consensus CDS ProjectCCDS37858.1
International Mouse Knockout Project StatusMyo5b
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000029560 VEGA Gene Model | MGI Sequence Detail 330558 C57BL/6J ±  kb
transcript OTTMUST00000073304 VEGA | MGI Sequence Detail 6065 Not Applicable 
polypeptide OTTMUSP00000037920 VEGA | MGI Sequence Detail 1844 Not Applicable 

For the selected sequences
All sequences(88) RefSeq(9) UniProt(7)
Polymorphisms RFLP(2) : SNPs within 2kb(3382 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR018444 Dil domain
InterPro IPR002710 Dilute
InterPro IPR000048 IQ motif, EF-hand binding site
InterPro IPR001609 Myosin head, motor domain
InterPro IPR027417 P-loop containing nucleoside triphosphate hydrolase
InterPro IPR016038 Thiolase-like, subgroup
Protein Ontology PR:000010866 myosin-Vb
References (Earliest) J:36578 Huang WM, et al., Molecular cloning and amino acid sequence of brain L-glutamate decarboxylase. Proc Natl Acad Sci U S A. 1990 Nov;87(21):8491-5
(Latest) J:201642 Holubcova Z, et al., Vesicles modulate an actin network for asymmetric spindle positioning. Nat Cell Biol. 2013 Aug;15(8):937-47
All references(45)
Other
accession IDs
MGD-MRK-35054, MGI:2147254

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
07/15/2014
MGI 5.18
The Jackson Laboratory