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Ddx6
Gene Detail
Symbol

Name
ID
Ddx6
DEAD (Asp-Glu-Ala-Asp) box polypeptide 6
MGI:104976
Synonyms
1110001P04Rik, C430015D01Rik, E230023J21Rik, HLR2, mRCK/P54, p54, rck
Feature Type
protein coding gene
Genetic Map
Chromosome 9
24.84 cM, cytoband B
Detailed Genetic Map ± 1 cM


Mapping data(4)
Sequence Map
Chr9:44604892-44640731 bp, + strand
From Ensembl annotation of GRCm38

  35840 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
Protein SuperFamily: ATP-dependent RNA helicase DHH1
Gene Tree: Ddx6
Mutations,
alleles, and
phenotypes
All mutations/alleles(100) : Gene trapped(98) Targeted(2)
Incidental mutations (data from Mutagenetix , APF )
Interactions
Ddx6 interacts with 482 markers (Mir1a-2, Mir1b, Mir7-1, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (11 annotations)
Process cytoplasmic mRNA processing body assembly
Component cytoplasm, cytoplasmic mRNA processing body, ...
Function ATP binding, helicase activity, ...
External Resources: FuncBase
Expression
Literature Summary: (8 records)
Data Summary: Results (42)    Tissues (9)    Images (7)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 20
Northern blot 6
RT-PCR 16
cDNA source data(121)
External Resources: Allen Institute   Expression Atlas
Molecular
reagents
All nucleic(139) Genomic(10) cDNA(123) Primer pair(5) Other(1)
Microarray probesets(6)
Other database
links
Ensembl Gene ModelENSMUSG00000032097 (Evidence)
Entrez Gene102637937, 13209
UniGene267061
DFCITC1609037, TC1579438, TC1686126, TC1651300, TC1631917
DoTSDT.87050229, DT.534646, DT.97365528, DT.91330726
NIA Mouse Gene IndexU010397, U052832, U010398
EC3.6.4.13
Consensus CDS ProjectCCDS23116.1
International Mouse Knockout Project StatusDdx6
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000032097 Ensembl Gene Model | MGI Sequence Detail 35840 C57BL/6J ±  kb
transcript ENSMUST00000170489 Ensembl | MGI Sequence Detail 6065 Not Applicable 
polypeptide ENSMUSP00000128421 Ensembl | MGI Sequence Detail 483 Not Applicable 

For the selected sequences
All sequences(26) UniProt(1)
Polymorphisms
RFLP(2) : SNPs within 2kb(239 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR011545 DNA/RNA helicase, DEAD/DEAH box type, N-terminal
InterPro IPR001650 Helicase, C-terminal
InterPro IPR014001 Helicase, superfamily 1/2, ATP-binding domain
InterPro IPR027417 P-loop containing nucleoside triphosphate hydrolase
InterPro IPR000629 RNA helicase, ATP-dependent, DEAD-box, conserved site
InterPro IPR014014 RNA helicase, DEAD-box type, Q motif
Protein Ontology PR:000029398 ATP-dependent RNA helicase DDX6
References
(Earliest) J:30308 Seto M, et al., Cloning and expression of a murine cDNA homologous to the human RCK/P54, a lymphoma-linked chromosomal translocation junction gene on 11q23. Gene. 1995 Dec 12;166(2):293-6
(Latest) J:182956 Saito K, et al., MicroRNA 130 family regulates the hypoxia response signal through the P-body protein DDX6. Nucleic Acids Res. 2011 Aug;39(14):6086-99
All references(51)
Other
accession IDs
MGD-MRK-31049, MGI:1923546, MGI:1925955, MGI:2444175

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
12/09/2014
MGI 5.20
The Jackson Laboratory