Homozygous mutants have increased body weight, enlargement of major organs, impaired hearing and increased tumor susceptibility. Females are sterile, having impaired luteal cell differentiation and disrupted estrus cycle.
|Process||activation of cysteine-type endopeptidase activity involved in apoptotic process, autophagic cell death, ...|
|Component||cytoplasm, cytosol, ...|
|Function||chaperone binding, cyclin-dependent protein serine/threonine kinase inhibitor activity, ...|
|RNA in situ||74|
|VEGA Gene Model||OTTMUSG00000021172 (Evidence)|
|Ensembl Gene Model||ENSMUSG00000003031 (Evidence)|
|Entrez Gene||12576 (Evidence)|
|DoTS||DT.101195241, DT.94249551, DT.40138623, DT.101206299, DT.101286163, DT.101286162|
|Consensus CDS Project||CCDS20642.1|
|International Mouse Phenotyping Consortium Status||Cdkn1b|
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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