cyclin-dependent kinase inhibitor 1B
Homozygous mutants have increased body weight, enlargement of major organs, impaired hearing and increased tumor susceptibility. Females are sterile, having impaired luteal cell differentiation and disrupted estrus cycle.
|Process||activation of cysteine-type endopeptidase activity involved in apoptotic process, autophagic cell death, ...|
|Component||cytoplasm, cytosol, ...|
|Function||chaperone binding, cyclin-dependent protein serine/threonine kinase inhibitor activity, ...|
|VEGA Gene Model||OTTMUSG00000021172 (Evidence)|
|Ensembl Gene Model||ENSMUSG00000003031 (Evidence)|
|Entrez Gene||12576 (Evidence)|
|DoTS||DT.101195241, DT.101206299, DT.101286162, DT.101286163, DT.40138623, DT.94249551|
|Consensus CDS Project||CCDS20642.1|
|International Mouse Knockout Project Status||Cdkn1b|
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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