Mice homozygous for a targeted mutation of this gene are viable and healthy but develop epileptic activity as well as reduced theta burst-induced LTP and NMDA receptor-mediated synaptic transmission in the CA1 field of the hippocampus; notably, homozygous mutant males are infertile.
|VEGA Gene Model||OTTMUSG00000021751 (Evidence)|
|Ensembl Gene Model||ENSMUSG00000026249 (Evidence)|
|Entrez Gene||20720 (Evidence)|
|DoTS||DT.101712051, DT.533874, DT.101405545|
|NIA Mouse Gene Index||U021518|
|Consensus CDS Project||CCDS15092.1|
|International Mouse Phenotyping Consortium Status||Serpine2|
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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