Phenotype Images associated with this Gene

About Help FAQ

Phenotype Images associated with this Gene

Symbol
Name
ID

Cdkn2a
cyclin dependent kinase inhibitor 2A
MGI:104738

Click on thumbnail to view full size image with links to phenotype annotations.
Click on allele symbol for full phenotype details.

	Caption: Pancreatic tumors in Kras^tm4Tyj/Kras^tm4Tyj Trim33^tm1Los/Trim33^tm1Los Tg(Pdx1-cre)89.1Dam/0 and Kras^tm4Tyj/Kras^tm4Tyj Cdkn2a^tm4Rdp/Cdkn2a^tm4Rdp Tg(Pdx1-cre)89.1Dam/0 mice (details) Represented Alleles: Cdkn2a^tm4Rdp, cyclin dependent kinase inhibitor 2A; targeted mutation 4, Ronald DePinho Kras^tm4Tyj, Kirsten rat sarcoma viral oncogene homolog; targeted mutation 4, Tyler Jacks Tg(Pdx1-cre)89.1Dam, transgene insertion 89.1, Douglas A Melton Trim33^tm1Los, tripartite motif-containing 33; targeted mutation 1, Regine Losson Copyright: This image is from Vincent DF, PLoS Genet 2009 Jul;5(7):e1000575, and is displayed under the terms of the Creative Commons Attribution 4.0 International License. J:151781
	Caption: Degenerative phenotypes, including increased apoptosis in gastrointestinal crypts and germ cell depletion, in Terc^tm1Rdp/Terc^tm1Rdp and Cdkn2a^tm1Rdp/Cdkn2a^tm1Rdp Terc^tm1Rdp/Terc^tm1Rdp mice (details) Represented Alleles: Cdkn2a^tm1Rdp, cyclin dependent kinase inhibitor 2A; targeted mutation 1, Ronald DePinho Terc^tm1Rdp, telomerase RNA component; targeted mutation 1, Ronald DePinho Copyright: This image is from Khoo CM, Proc Natl Acad Sci U S A 2007 Mar 6;104(10):3931-6. Copyright 2007 National Academy of Sciences, U.S.A. J:120065
	Caption: Metastasis of primary squamous cell carcinoma to lymph nodes and lungs in Cdkn2a^tm1Cjs/Cdkn2a^tm1Cjs mice (details) Represented Alleles: Cdkn2a^tm1Cjs, cyclin dependent kinase inhibitor 2A; targeted mutation 1, Charles J Scherr Copyright: This image is from Kelly-Spratt KS, PLoS Biol 2004 Sep;2(8):E242, and is displayed under the terms of the Creative Commons Attribution 4.0 International License. J:93298
	Caption: Tumor multiplicity and proliferation index in Cdkn2a^tm1Cjs/Cdkn2a^tm1Cjs, Trp53^tm1Brd/Trp53^tm1Brd and Cdkn2a^tm1Cjs/Cdkn2a^tm1Cjs Trp53^tm1Brd/Trp53^tm1Brd mice (details) Represented Alleles: Cdkn2a^tm1Cjs, cyclin dependent kinase inhibitor 2A; targeted mutation 1, Charles J Scherr Trp53^tm1Brd, transformation related protein 53; targeted mutation 1, Allan Bradley Copyright: This image is from Kelly-Spratt KS, PLoS Biol 2004 Sep;2(8):E242, and is displayed under the terms of the Creative Commons Attribution 4.0 International License. J:93298
	Caption: Abnormal retrolental tissue present in the eyes of neonatal Cdkn2a^tm1Cjs/Cdkn2a^tm1Cjs mice (details) Represented Alleles: Cdkn2a^tm1Cjs, cyclin dependent kinase inhibitor 2A; targeted mutation 1, Charles J Scherr Copyright: This image is from McKeller RN, Proc Natl Acad Sci U S A 2002 Mar 19;99(6):3848-53. Copyright 2002 National Academy of Sciences, U.S.A. J:75215
	Caption: Retrolental tissue in Cdkn2a^tm1Cjs/Cdkn2a^tm1Cjs mice contains mature hyaloid vascular structures and endothelial cells (details) Represented Alleles: Cdkn2a^tm1Cjs, cyclin dependent kinase inhibitor 2A; targeted mutation 1, Charles J Scherr Copyright: This image is from McKeller RN, Proc Natl Acad Sci U S A 2002 Mar 19;99(6):3848-53. Copyright 2002 National Academy of Sciences, U.S.A. J:75215
	Caption: PHPV-like abnormalities develop in Cdkn2a^tm1Cjs/Cdkn2a^tm1Cjs mouse eyes (details) Represented Alleles: Cdkn2a^tm1Cjs, cyclin dependent kinase inhibitor 2A; targeted mutation 1, Charles J Scherr Copyright: This image is from McKeller RN, Proc Natl Acad Sci U S A 2002 Mar 19;99(6):3848-53. Copyright 2002 National Academy of Sciences, U.S.A. J:75215
	Caption: Persistent hyperplastic primary vitreous (PHPV) in Cdkn2a^tm1Cjs/Cdkn2a^tm1Cjs mice is p53 independent (details) Represented Alleles: Cdkn2a^tm1Cjs, cyclin dependent kinase inhibitor 2A; targeted mutation 1, Charles J Scherr Trp53^tm1Tyj, transformation related protein 53; targeted mutation 1, Tyler Jacks Copyright: This image is from McKeller RN, Proc Natl Acad Sci U S A 2002 Mar 19;99(6):3848-53. Copyright 2002 National Academy of Sciences, U.S.A. J:75215

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 04/30/2024 MGI 6.23