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Phenotype Images associated with this Allele
Nomenclature
Symbol: Ptentm1Hwu
Name: phosphatase and tensin homolog; targeted mutation 1, Hong Wu
MGI ID: MGI:2156086
Synonyms: Ptenex5lox, PTENF, Ptenfl, Ptenflox, Ptenfx, Ptenlox, Ptenloxp
Images for
Allele
Click images for details
Image Caption Genotypes involving this allele
Allelic Composition Genetic Background
Tgfbr1tm1.1Karl/Tgfbr1tm1.1Karl Ptentm1Hwu/Ptentm1Hwu Tg(KRT14-cre/ERT)20Efu/0 mice develop anal squamous cell carcinomaPtentm1Hwu/Ptentm1Hwu
Tgfbr1tm1.1Karl/Tgfbr1tm1.1Karl
Tg(KRT14-cre/ERT)20Efu/0
involves: 129 * 129S4/SvJae * C57BL/6 * CD-1 * FVB/N
Increase in mesenchymal cell proliferation in Ptentm1Hwu/Ptentm1Hwu Twist2tm1.1(cre)Dor/Twist2+ micePtentm1Hwu/Ptentm1Hwu
Twist2tm1.1(cre)Dor/Twist2+
B6.129-Twist2tm1.1(cre)Dor Ptentm1Hwu
Abnormal airway capillary coupling in Ptentm1Hwu/Ptentm1Hwu Twist2tm1.1(cre)Dor/Twist2+ micePtentm1Hwu/Ptentm1Hwu
Twist2tm1.1(cre)Dor/Twist2+
B6.129-Twist2tm1.1(cre)Dor Ptentm1Hwu
Defect in angioblast differentiation in Ptentm1Hwu/Ptentm1Hwu Kdrtm1Jrt/Kdr+ Twist2tm1.1(cre)Dor/Twist2+ miceKdrtm1Jrt/Kdr+
Ptentm1Hwu/Ptentm1Hwu
Twist2tm1.1(cre)Dor/Twist2+
B6.129-Twist2tm1.1(cre)Dor Kdrtm1Jrt Ptentm1Hwu
Vascular defects in Ptentm1Hwu/Ptentm1Hwu Twist2tm1.1(cre)Dor/Twist2+ embryosPtentm1Hwu/Ptentm1Hwu
Twist2tm1.1(cre)Dor/Twist2+
B6.129-Twist2tm1.1(cre)Dor Ptentm1Hwu
Generalized lack of vascularization in Ptentm1Hwu/Ptentm1Hwu Twist2tm1.1(cre)Dor/Twist2+ micePtentm1Hwu/Ptentm1Hwu
Twist2tm1.1(cre)Dor/Twist2+
B6.129-Twist2tm1.1(cre)Dor Ptentm1Hwu
Ovary tumors in Pik3catm1.1Waph/Pik3catm1.1Waph Ptentm1Hwu/Ptentm1Hwu micePik3catm1.1Waph/Pik3ca+
Ptentm1Hwu/Ptentm1Hwu
involves: 129S1/Sv * 129S4/SvJae * BALB/c * C57BL/6

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
04/26/2016
MGI 6.03
The Jackson Laboratory