EZH2 Vertebrate HGNC

Vertebrate Homology

Source

Alliance of Genome Resources

Comparative GO Graph (mouse, human, rat, zebrafish)

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences select all deselect all Go
human	EZH2	HGNC:3527 (HGNC) 2146 (Entrez Gene) 601573 (OMIM) EZH2 (Alliance of Genome Resources)	Chr7 q36.1	Chr7:148807257-148884321 (-) GRCh38	acute megakaryocytic leukemia acute myeloid leukemia B-cell lymphoma cholangiocarcinoma chronic myelomonocytic leukemia colorectal adenocarcinoma colorectal cancer congestive heart failure glioblastoma hepatocellular carcinoma lung cancer myelodysplastic syndrome myelofibrosis oral squamous cell carcinoma osteosarcoma renal Wilms' tumor stomach cancer Weaver syndrome	Q15910 (UniProt \| EBI) NM_001203247 (RefSeq)
mouse	Ezh2	MGI:107940 (MGI) 14056 (Entrez Gene) Gene Tree Ezh2 (Alliance of Genome Resources)	Chr6 22.92 cM	Chr6:47507073-47572275 (-) GRCm39	acute lymphoblastic leukemia B-cell lymphoma Weaver syndrome	ENSMUSG00000029687 (Ensembl Gene Model) ENSMUSP00000080419 (Ensembl) ENSMUST00000081721 (Ensembl)
rat	Ezh2	RGD:1595860 (Rat Genome Database) 312299 (Entrez Gene) Ezh2 (Alliance of Genome Resources)	Chr4 q24			NP_001128451 (RefSeq) NM_001134979 (RefSeq)
zebrafish	ezh2	ZDB-GENE-041111-259 (Zebrafish Model Organism Database) 768133 (Entrez Gene) ezh2 (Alliance of Genome Resources)	Chr24			Q08BS4 (UniProt \| EBI) NM_001077279 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
- human
- mouse
- rat
- zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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