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Comparative GO Graph (mouse, human, rat, zebrafish)
Source
Alliance of Genome Resources

Compare experimental GO annotations for Human-Mouse-Rat-Zebrafish orthologs to Mouse Klf6

Graphs for Molecular Function, Cellular Component, Biological Process generated Mon Apr 26 17:39:58 2021.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

Molecular Function


Cellular Component


Biological Process



Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Klf6
Category ID Classification term Gene Evidence Inferred from Organism Reference
Molecular FunctionGO:0003682chromatin bindingklf6aIDAZfishPMID:26015096|ZFIN:ZDB-PUB-150528-4
Molecular FunctionGO:0000987cis-regulatory region sequence-specific DNA bindingklf6aIDAZfishPMID:20123021|ZFIN:ZDB-PUB-100211-4
Molecular FunctionGO:0001228DNA-binding transcription activator activity, RNA polymerase II-specificKLF6IDAHumanPMID:18755691
Molecular FunctionGO:0003700DNA-binding transcription factor activityKlf6IDARatPMID:9689109|RGD:62381
Molecular FunctionGO:0000981DNA-binding transcription factor activity, RNA polymerase II-specificklf6aIDAZfishPMID:28803829|ZFIN:ZDB-PUB-170815-11
Molecular FunctionGO:0001227DNA-binding transcription repressor activity, RNA polymerase II-specificklf6aIDAZfishPMID:26015096|ZFIN:ZDB-PUB-150528-4
Molecular FunctionGO:0003690double-stranded DNA bindingKlf6IDARatPMID:9689109|RGD:62381
Molecular FunctionGO:0005515protein bindingKLF6IPIUniProtKB:Q04206HumanPMID:24634218
Molecular FunctionGO:0005515protein bindingKLF6IPIUniProtKB:P02545HumanPMID:32814053
Molecular FunctionGO:0005515protein bindingKLF6IPIUniProtKB:P41250HumanPMID:32814053
Molecular FunctionGO:0005515protein bindingKLF6IPIUniProtKB:Q7Z699HumanPMID:32814053
Molecular FunctionGO:0000978RNA polymerase II cis-regulatory region sequence-specific DNA bindingKLF6IDAHumanPMID:18755691
Molecular FunctionGO:1990837sequence-specific double-stranded DNA bindingKLF6IDAHumanPMID:28473536
Cellular ComponentGO:0000785chromatinklf6aIDAZfishPMID:28803829|ZFIN:ZDB-PUB-170815-11
Cellular ComponentGO:0005737cytoplasmKlf6IDAMouseMGI:MGI:3522536|PMID:15557439
Cellular ComponentGO:0005829cytosolKLF6IDAHumanGO_REF:0000052
Cellular ComponentGO:0001650fibrillar centerKLF6IDAHumanGO_REF:0000052
Cellular ComponentGO:0043231intracellular membrane-bounded organelleKLF6IDAHumanGO_REF:0000052
Cellular ComponentGO:0005730nucleolusKLF6IDAHumanGO_REF:0000052
Cellular ComponentGO:0005654nucleoplasmKLF6IDAHumanGO_REF:0000052
Cellular ComponentGO:0005634nucleusKlf6IDAMouseMGI:MGI:3522536|PMID:15557439
Cellular ComponentGO:0005634nucleusKlf6IDARatPMID:9689109|RGD:62381
Biological ProcessGO:0071409cellular response to cycloheximideKlf6IEPRatPMID:18406357|RGD:2316543
Biological ProcessGO:0070301cellular response to hydrogen peroxideKlf6IEPRatPMID:18406357|RGD:2316543
Biological ProcessGO:0071407cellular response to organic cyclic compoundKlf6IEPRatPMID:18406357|RGD:2316543
Biological ProcessGO:1901653cellular response to peptideKlf6IEPRatPMID:18406357|RGD:2316543
Biological ProcessGO:0019221cytokine-mediated signaling pathwayKlf6IDAMouseMGI:MGI:1929944|PMID:10880228
Biological ProcessGO:0048565digestive tract developmentklf6aIMPZFIN:ZDB-MRPHLNO-100811-7ZfishPMID:20430021|ZFIN:ZDB-PUB-100504-13
Biological ProcessGO:0048565digestive tract developmentklf6aIMPZFIN:ZDB-MRPHLNO-100811-6ZfishPMID:20430021|ZFIN:ZDB-PUB-100504-13
Biological ProcessGO:0043249erythrocyte maturationklf6aIMPZFIN:ZDB-MRPHLNO-080208-5ZfishPMID:26015096|ZFIN:ZDB-PUB-150528-4
Biological ProcessGO:0001889liver developmentklf6aIMPZFIN:ZDB-MRPHLNO-100811-6ZfishPMID:20430021|ZFIN:ZDB-PUB-100504-13
Biological ProcessGO:0001889liver developmentklf6aIMPZFIN:ZDB-MRPHLNO-100811-7ZfishPMID:20430021|ZFIN:ZDB-PUB-100504-13
Biological ProcessGO:0021634optic nerve formationklf6aIDAZfishPMID:20123021|ZFIN:ZDB-PUB-100211-4
Biological ProcessGO:0035265organ growthklf6aIMPZFIN:ZDB-MRPHLNO-100811-6ZfishPMID:20430021|ZFIN:ZDB-PUB-100504-13
Biological ProcessGO:0035265organ growthklf6aIMPZFIN:ZDB-MRPHLNO-100811-7ZfishPMID:20430021|ZFIN:ZDB-PUB-100504-13
Biological ProcessGO:0031016pancreas developmentklf6aIMPZFIN:ZDB-MRPHLNO-100811-7ZfishPMID:20430021|ZFIN:ZDB-PUB-100504-13
Biological ProcessGO:0031016pancreas developmentklf6aIMPZFIN:ZDB-MRPHLNO-100811-6ZfishPMID:20430021|ZFIN:ZDB-PUB-100504-13
Biological ProcessGO:1905205positive regulation of connective tissue replacementKlf6IMPMouseMGI:MGI:5447902|PMID:22820290
Biological ProcessGO:0045944positive regulation of transcription by RNA polymerase IIKLF6IDAHumanPMID:18755691
Biological ProcessGO:0045944positive regulation of transcription by RNA polymerase IIKlf6IDARatPMID:9689109|RGD:62381
Biological ProcessGO:2000471regulation of hematopoietic stem cell migrationklf6aIMPZFIN:ZDB-GENO-180215-3ZfishPMID:28803829|ZFIN:ZDB-PUB-170815-11
Biological ProcessGO:2000471regulation of hematopoietic stem cell migrationklf6aIGIZFIN:ZDB-GENE-110222-2ZfishPMID:28803829|ZFIN:ZDB-PUB-170815-11
Biological ProcessGO:1902033regulation of hematopoietic stem cell proliferationklf6aIMPZFIN:ZDB-GENO-180215-3ZfishPMID:28803829|ZFIN:ZDB-PUB-170815-11
Biological ProcessGO:1902033regulation of hematopoietic stem cell proliferationklf6aIGIZFIN:ZDB-GENE-110222-2ZfishPMID:28803829|ZFIN:ZDB-PUB-170815-11
Biological ProcessGO:0006357regulation of transcription by RNA polymerase IIklf6aIDAZfishPMID:28803829|ZFIN:ZDB-PUB-170815-11
Biological ProcessGO:0042060wound healingKlf6IEPRatPMID:9689109|RGD:62381

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment
  IDA Inferred from direct assay
  IEP Inferred from expression pattern
  IGI Inferred from genetic interaction
  IMP Inferred from mutant phenotype
  IPI Inferred from physical interaction
  HTP Inferred from High Throughput Experiment
  HDA Inferred from High Throughput Direct Assay
  HMP Inferred from High Throughput Mutant Phenotype
  HGI Inferred from High Throughput Genetic Interaction
  HEP Inferred from High Throughput Expression Pattern

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
11/23/2021
MGI 6.17
The Jackson Laboratory