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Phenotypes Associated with This Genotype
Genotype
MGI:5824005
Allelic
Composition
Stk3tm1Jav/Stk3tm1Jav
Stk4Gt(AJ0315)Wtsi/Stk4Gt(AJ0315)Wtsi
Speer6-ps1Tg(Alb-cre)21Mgn/Speer6-ps1+
Genetic
Background
involves: 129 * 129P2/OlaHsd * C57BL/6 * DBA
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Speer6-ps1Tg(Alb-cre)21Mgn mutation (5 available); any Speer6-ps1 mutation (2 available)
Stk3tm1Jav mutation (0 available); any Stk3 mutation (12 available)
Stk4Gt(AJ0315)Wtsi mutation (0 available); any Stk4 mutation (19 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
liver/biliary system
• mice develop multiple spontaneous hepatocellular carcinomas

neoplasm
• mice develop multiple spontaneous hepatocellular carcinomas

Mouse Models of Human Disease
DO ID OMIM ID(s) Ref(s)
hepatocellular carcinoma DOID:684 OMIM:114550
J:238319


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
11/05/2019
MGI 6.14
The Jackson Laboratory