Phenotypes associated with this allele
immune system
|
N |
• LPS-induced monocyte emigration is normal
|
|
|
| Find Mice |
Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ccl2tm1.1Pame mutation
(1 available);
any
Ccl2 mutation
(25 available)
Tg(Tek-cre)12Flv mutation
(1 available)
|
|
|
immune system
|
|
• LPS-induced monocyte emigration is decreased compared to in similarly treated wild-type mice
• mice exposed to L. monocytogenes exhibit reduced Ly6Chi monocyte emigration from the bone marrow compared with similarly treated wild-type mice
|
|
|
• mice exposed to L. monocytogenes exhibit reduced Ly6Chi monocyte emigration from the bone marrow compared with similarly treated wild-type mice
|
cellular
|
|
• LPS-induced monocyte emigration is decreased compared to in similarly treated wild-type mice
• mice exposed to L. monocytogenes exhibit reduced Ly6Chi monocyte emigration from the bone marrow compared with similarly treated wild-type mice
|
hematopoietic system
|
|
• LPS-induced monocyte emigration is decreased compared to in similarly treated wild-type mice
• mice exposed to L. monocytogenes exhibit reduced Ly6Chi monocyte emigration from the bone marrow compared with similarly treated wild-type mice
|
immune system
|
N |
• LPS-induced monocyte emigration is normal
|
|
|
| Find Mice |
Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ccl2tm1.1Pame mutation
(1 available);
any
Ccl2 mutation
(25 available)
Tg(Nes-cre)1Kln mutation
(4 available)
|
|
|
immune system
|
|
• LPS-treated mice exhibit reduced percent of circulating Ly6Chi monocyte compared with similarly treated wild-type mice
• mice exposed to L. monocytogenes exhibit reduced Ly6Chi monocyte emigration from the bone marrow compared with similarly treated wild-type mice
|
|
|
• mice exposed to L. monocytogenes exhibit reduced Ly6Chi monocyte emigration from the bone marrow and diminished bacterial clearance compared with similarly treated wild-type mice
|
cellular
|
|
• LPS-treated mice exhibit reduced percent of circulating Ly6Chi monocyte compared with similarly treated wild-type mice
• mice exposed to L. monocytogenes exhibit reduced Ly6Chi monocyte emigration from the bone marrow compared with similarly treated wild-type mice
|
hematopoietic system
|
|
• LPS-treated mice exhibit reduced percent of circulating Ly6Chi monocyte compared with similarly treated wild-type mice
• mice exposed to L. monocytogenes exhibit reduced Ly6Chi monocyte emigration from the bone marrow compared with similarly treated wild-type mice
|
Analysis Tools