• absence of vas deferens

• XY male mice developed undescended dysfunctional testes, uteri, coiled oviducts, and a vagina with an opening

• Mullerian duct derivatives were absent (J:83429)

• there is no tight attachment of the testes to the inguinal region (J:83429)

• bilateral cryptorchism with testes situated adjacent to the kidneys (J:83429)

• lack of tight attachment to the inguinal region (J:83429)

• testes were attached to the dorsal abdominal wall by well developed cranial suspsensory ligaments (J:83429)

• the epididymis was absent (J:83429)

• the vas deferens was absent (J:83429)

• the male external and internal genitalia are not virilized (J:83429)

• bilateral cryptorchism with testes situated adjacent to the kidneys (J:83429)

• lack of tight attachment to the inguinal region (J:83429)

• testes were attached to the dorsal abdominal wall by well developed cranial suspsensory ligaments (J:83429)

• there is no tight attachment of the testes to the inguinal region (J:83429)

• mice survive at least 200 days unlike Lactb2^{Tg(Igh-Meis1)2770Amb} homozygotes (J:79618)

• mice exhibit greater thickening and hyperplasia of peritubular myoid cells compared to Ar^Tfm male mice on the original stock background

• unlike Ar^Tfm male mice on the original stock background

• in 8 of 31 mice unlike Ar^Tfm male mice on the original stock background

• compared to Ar^Tfm male mice on a mixed NMRI and stock of origin background

• spermatogenesis does not proceed beyond meiosis prophase

• male mice have female genitals, a blind ending vagina, inguinal testes, no scrotum and lack derivatives of the Wolffian ducts

• 3 of 31 mice exhibit unilateral Leydig tumor unlike Ar^Tfm male mice on the original stock background

• however, no germ cell tumors are observed

• mice exhibit greater thickening and hyperplasia of peritubular myoid cells compared to Ar^Tfm male mice on the original stock background

• unlike Ar^Tfm male mice on the original stock background

• in 8 of 31 mice unlike Ar^Tfm male mice on the original stock background

• compared to Ar^Tfm male mice on a mixed NMRI and stock of origin background

• Background Sensitivity: mice exhibit greater thickening and hyperplasia of peritubular myoid cells compared to Ar^Tfm male mice on the original stock background

• Background Sensitivity: unlike Ar^Tfm male mice on the original stock background

• Background Sensitivity: in 15 of 46 mice unlike Ar^Tfm male mice on the original stock background

• spermatogenesis does not proceed beyond meiosis prophase

• male mice have female genitals, a blind ending vagina, inguinal testes, no scrotum and lack derivatives of the Wolffian ducts

• Background Sensitivity: 4 of 46 mice exhibit unilateral Leydig tumor unlike Ar^Tfm male mice on the original stock background

• however, no germ cell tumors are observed

• Background Sensitivity: mice exhibit greater thickening and hyperplasia of peritubular myoid cells compared to Ar^Tfm male mice on the original stock background

• Background Sensitivity: unlike Ar^Tfm male mice on the original stock background

• Background Sensitivity: in 15 of 46 mice unlike Ar^Tfm male mice on the original stock background

• Background Sensitivity: mice exhibit thickening and hyperplasia of peritubular myoid cells that is not as great as when the allele is present on a mixed NMRI and stock of origin background

• spermatogenesis does not proceed beyond meiosis prophase

• male mice have female genitals, a blind ending vagina, inguinal testes, no scrotum and lack derivatives of the Wolffian ducts

• Background Sensitivity: mice exhibit thickening and hyperplasia of peritubular myoid cells that is not as great as when the allele is present on a mixed NMRI and stock of origin background

• increase in the percentage and absolute number of B cell precursors

• however, the number of LPS responsive B cells is not increased

• the percentage of TER119+ cells in the bone marrow is decreased

• however, the number of circulating TER119+ cells is not significantly different from controls

• the number of MAC-1+ cells in the bone marrow is decreased

• however, the number of circulating MAC-1+ cells is not significantly different from controls

• the number of MAC-1+ cells in the bone marrow is decreased

• the percentage of TER119+ cells in the bone marrow is decreased

• increase in the percentage and absolute number of B cell precursors

• however, the number of LPS responsive B cells is not increased

• the number of MAC-1+ cells in the bone marrow is decreased

• however, the number of circulating MAC-1+ cells is not significantly different from controls

• increase in the percentage and absolute number of B cell precursors

• however, the number of LPS responsive B cells is not increased

• an extra layer of parietal lymphatic cells was present, but these cells appeared to be normal; myoid cells were also normal (J:65900)

• peritubular fibrosis was observed, as indicated by a few extra layers of fibroblastic-like cells around the seminiferous tubules, although this fibrosis was not as severe as that seen in Dhh^tm1Amc feminized males (J:65900)

• collagen and basal lamina material between Sertoli and myoid cells extended around the entire seminiferous tubule unlike that of the patchy basal lamina seen in Dhh^tm1Amc feminized males (J:65900)

• at 63 days of age, testes from adult male hemizygotes contained abundant adult-type Leydig cells which appeared relatively undifferentiated and lacked smooth endoplasmic reticulum (J:65900)

• germ cell development progressed to spermatocytes (J:65900)

• an extra layer of parietal lymphatic cells was present, but these cells appeared to be normal; myoid cells were also normal (J:65900)

• peritubular fibrosis was observed, as indicated by a few extra layers of fibroblastic-like cells around the seminiferous tubules, although this fibrosis was not as severe as that seen in Dhh^tm1Amc feminized males (J:65900)

• collagen and basal lamina material between Sertoli and myoid cells extended around the entire seminiferous tubule unlike that of the patchy basal lamina seen in Dhh^tm1Amc feminized males (J:65900)

• at 63 days of age, testes from adult male hemizygotes contained abundant adult-type Leydig cells which appeared relatively undifferentiated and lacked smooth endoplasmic reticulum (J:65900)

• indistinguishable from females

• XY mice had vaginas that remained closed in most mice, though some did open at 3 months of age

• most spermatocytes were arrested at meiotic prophase, though some were observed in metaphase

• hypertrophic

• testes were positioned amongst fat in the abdomen

• the epididymides were absent from XY mice

• the vas deferens were absent from XY mice

• XY mice possessed testes and female secondary structures including vagina and teats

• XY mice did not possess ovaries

• XY mice behaved like non-oestrus females, reduced aggression

• indistinguishable from females

• hypertrophic

• testes were positioned amongst fat in the abdomen