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Cgref1 Gene Detail
Summary
  • Symbol
    Cgref1
  • Name
    cell growth regulator with EF hand domain 1
  • Synonyms
    1110004G24Rik, CGR11
  • Feature Type
    protein coding gene
  • IDs
    MGI:1915817
    NCBI Gene: 68567
  • Alliance
    gene page
  • Transcription Start Sites
    7 TSS
Location &
Maps
more
  • Sequence Map
    Chr5:31090487-31102771 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 5, 16.90 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    406 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1915817
 protein coding gene Chr5:31090487-31102935 (-)
129S1/SvImJ MGP_129S1SvImJ_G0029402
 protein coding gene Chr5:28891858-28904842 (-)
A/J MGP_AJ_G0029368
 protein coding gene Chr5:27955220-27968081 (-)
AKR/J MGP_AKRJ_G0029319
 protein coding gene Chr5:29106581-29119446 (-)
BALB/cJ MGP_BALBcJ_G0029379
 protein coding gene Chr5:28476385-28488566 (-)
C3H/HeJ MGP_C3HHeJ_G0029100
 protein coding gene Chr5:29104639-29117925 (-)
C57BL/6NJ MGP_C57BL6NJ_G0029832
 protein coding gene Chr5:30672400-30684848 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0027070
 protein coding gene Chr5:25433425-25444494 (-)
CAST/EiJ MGP_CASTEiJ_G0028511
 protein coding gene Chr5:28198937-28212562 (-)
CBA/J MGP_CBAJ_G0029068
 protein coding gene Chr5:31243912-31255564 (-)
DBA/2J MGP_DBA2J_G0029217
 protein coding gene Chr5:28137228-28148888 (-)
FVB/NJ MGP_FVBNJ_G0029175
 protein coding gene Chr5:27550886-27562660 (-)
LP/J MGP_LPJ_G0029302
 protein coding gene Chr5:29355724-29367407 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0029204
 protein coding gene Chr5:32136993-32149930 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0029866
 protein coding gene Chr5:28608460-28620121 (-)
PWK/PhJ MGP_PWKPhJ_G0028235
 protein coding gene Chr5:27255084-27266601 (-)
SPRET/EiJ MGP_SPRETEiJ_G0028065
 protein coding gene Chr5:27980284-27992820 (-)
WSB/EiJ MGP_WSBEiJ_G0028591
 protein coding gene Chr5:28671831-28684493 (-)



Homology
more
  • Human Ortholog
    CGREF1, cell growth regulator with EF-hand domain 1
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    CGREF1, cell growth regulator with EF-hand domain 1
  • Synonyms
    CGR11
  • Links
    NCBI Gene ID: 10669
    UniProt: Q99674

  • Chr Location
    2p23.3; chr2:27098889-27119128 (-)  GRCh38
Human Diseases
less
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    6 phenotypes from 1 allele in 1 genetic background
    26 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    1
  • GO References
    1
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

No experimental evidence to support Cellular Component annotation, following literature review. See J:73796.
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    1115
  • Tissues
    175
  • cDNA Data
    41
  • Literature Summary
    6
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 68567 NCBI Gene Model | MGI Sequence Detail 12285 C57BL/6J ±  kb
    transcript NM_001160149 RefSeq | MGI Sequence Detail 1266 C57BL/6  
    polypeptide Q8R1U2 UniProt | EBI | MGI Sequence Detail 281 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 43
      cDNA 41
      Primer pair 2

      Microarray probesets 5
    Other
    Accession IDs
    less
    MGI:2141124
    References
    more
    • Summaries
      All 53
      Developmental Gene Expression 6
      Diseases 1
      Gene Ontology 1
      Phenotypes 26
    • Earliest
      J:5021 Batchelor AL, et al., A comparison of the mutagenic effectiveness of chronic neutron- and gamma-irradiation of mouse spermatogonia. Mutat Res. 1966 Jun;3(3):218-29
    • Latest
      J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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    Funding Information
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    Send questions and comments to User Support.     		last database update
    03/25/2025
    MGI 6.24     		The Jackson Laboratory