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Gene Expression Data
Assay Details
Assay
Reference: J:197339 Pignon JC, et al., p63-expressing cells are the stem cells of developing prostate, bladder, and colorectal epithelia. Proc Natl Acad Sci U S A. 2013 May 14;110(20):8105-10
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7431428
Gene symbol: Trp63
Gene name: transformation related protein 63
Antibody: 4A4
Detection system: Secondary antibody coupled to Cy5
Results
Specimen 3A: embryonic day 13.5; Gt(ROSA)26Sortm1(EYFP)Cos/Gt(ROSA)26Sor+, Trp63tm1.1(cre)Ssig/Trp63+ (more )
Note: Conditional mutant. Triple labeled: red - Trp63; white - Upk3a (assay MGI:7431437); green - Cre reporter.
Structure Level Pattern Image Note
TS21: urothelium of primitive bladder Present 3A p63 , 3A Merge
Specimen 3B: embryonic day 15.5; Gt(ROSA)26Sortm1(EYFP)Cos/Gt(ROSA)26Sor+, Trp63tm1.1(cre)Ssig/Trp63+ (more )
Note: Conditional mutant. Triple labeled: red - Trp63; white - Upk3a (assay MGI:7431437); green - Cre reporter.
Structure Level Pattern Image Note
TS23: urothelium of bladder Present 3B p63 , 3B Merge Expression is in the basal and suprabasal layers.
Specimen 3C: postnatal day 7; Gt(ROSA)26Sortm1(EYFP)Cos/Gt(ROSA)26Sor+, Trp63tm1.1(cre)Ssig/Trp63+ (more )
Note: Conditional mutant. Triple labeled: red - Trp63; white - Upk3a (assay MGI:7431437); green - Cre reporter.
Structure Level Pattern Image Note
TS28: urothelium of bladder Present 3C p63 , 3C Merge
Specimen 4A: embryonic day 13.5; Gt(ROSA)26Sortm1(EYFP)Cos/Gt(ROSA)26Sor+, Trp63tm1.1(cre)Ssig/Trp63+ (more )
Note: Conditional mutant. Double labeled: red - Trp63; green - Cre reporter.
Structure Level Pattern Image Note
TS21: epithelium of urogenital sinus Present 4A Merge , 4A p63
Specimen 4B: embryonic day 15.5; Gt(ROSA)26Sortm1(EYFP)Cos/Gt(ROSA)26Sor+, Trp63tm1.1(cre)Ssig/Trp63+ (more )
Note: Conditional mutant. Double labeled: red - Trp63; green - Cre reporter.
Structure Level Pattern Image Note
TS23: epithelium of urogenital sinus Present 4B p63 , 4B Merge
Specimen 4C: postnatal day 0-1; Gt(ROSA)26Sortm1(EYFP)Cos/Gt(ROSA)26Sor+, Trp63tm1.1(cre)Ssig/Trp63+ (more )
Note: Conditional mutant. Double labeled: red - Trp63; green - Cre reporter.
Structure Level Pattern Image Note
TS27: prostate bud Present Graded 4C p63 red merge , 4C p63 red , 4C p63 blue , 4C p63 blue merge , 4C p63 There is a proximal-to-distal gradient of expression.
Specimen 4D: postnatal week 7; Gt(ROSA)26Sortm1(EYFP)Cos/Gt(ROSA)26Sor+, Trp63tm1.1(cre)Ssig/Trp63+ (more )
Note: Conditional mutant. Triple labeled: red - Trp63; white - Krt8 (assay MGI:7431440); green - Cre reporter.
Structure Level Pattern Image Note
TS28: prostate gland Present 4D Merge , 4D p63 , 4D
Specimen 5B 13.5: embryonic day 13.5; Gt(ROSA)26Sortm1(EYFP)Cos/Gt(ROSA)26Sor+, Trp63tm1.1(cre)Ssig/Trp63+ (more )
Note: Conditional mutant. Double labeled: red - Trp63; green - Cre reporter.
Structure Level Pattern Image Note
TS21: lower urinary tract Present Regionally restricted 5B 13.5 Expression is in the urorectal region.
TS21: hindgut Present Regionally restricted 5B 13.5 Expression is distal.
Specimen 5B 15.5: embryonic day 15.5; Gt(ROSA)26Sortm1(EYFP)Cos/Gt(ROSA)26Sor+, Trp63tm1.1(cre)Ssig/Trp63+ (more )
Note: Conditional mutant. Double labeled: red - Trp63; green - Cre reporter.
Structure Level Pattern Image Note
TS23: hindgut Present Regionally restricted 5B 15.5 Expression is distal.
Specimen S2B Dorsal: embryonic day 9.5; Gt(ROSA)26Sortm1(EYFP)Cos/Gt(ROSA)26Sor+, Trp63tm1.1(cre)Ssig/Trp63+ (more )
Note: Conditional mutant. Double labeled: red - Trp63; green - Cre reporter.
Structure Level Pattern Image Note
TS15: surface ectoderm Present S2B Dorsal Skin p63 , S2B Dorsal Skin merge
Specimen S2B Ventral: embryonic day 9.5; Gt(ROSA)26Sortm1(EYFP)Cos/Gt(ROSA)26Sor+, Trp63tm1.1(cre)Ssig/Trp63+ (more )
Note: Conditional mutant. Double labeled: red - Trp63; green - Cre reporter.
Structure Level Pattern Image Note
TS15: surface ectoderm Present S2B Ventral Skin merge , S2B Ventral Skin p63
Specimen S6A: embryonic day 13.5 (more )
Note: Triple labeled: red - Trp63; gray - Krt8 (assay MGI:7431440); green - Krt5 (assay MGI:7431454).
Structure Level Pattern Image Note
TS21: epithelium of urogenital sinus Present Uniform S6A Merge , S6A p63
Specimen S6B: embryonic day 15.5 (more )
Note: Triple labeled: red - Trp63; gray - Krt8 (assay MGI:7431440); green - Krt5 (assay MGI:7431454).
Structure Level Pattern Image Note
TS23: epithelium of urogenital sinus Present Regionally restricted S6B Merge , S6B p63 Expression is in basal and suprabasal cells.
Specimen S6C: postnatal day 0-1 (more )
Note: Triple labeled: red - Trp63; gray - Krt8 (assay MGI:7431440); green - Krt5 (assay MGI:7431454).
Structure Level Pattern Image Note
TS27: prostate bud Present Graded S6C Merge , S6C p63 There is a proximal-to-distal gradient of expression.
Specimen S6D: postnatal week 7 (more )
Note: Triple labeled: red - Trp63; gray - Krt8 (assay MGI:7431440); green - Krt5 (assay MGI:7431454).
Structure Level Pattern Image Note
TS28: prostate gland Present Regionally restricted S6D Merge , S6D p63 Expression is in prostate basal cells.
Specimen S7A: postnatal day 0-1; Gt(ROSA)26Sortm4(ACTB-tdTomato,-EGFP)Luo/Gt(ROSA)26Sor+, Trp63tm1.1(cre)Ssig/Trp63+ (more )
Note: Conditional mutant. Double labeled: red - Trp63; green - Cre reporter.
Structure Level Pattern Image Note
TS27: prostate bud Present S7A , S7A red p63 , S7A red merge , S7A blue merge , S7A blue p63
Specimen S7B: postnatal week 7; Gt(ROSA)26Sortm4(ACTB-tdTomato,-EGFP)Luo/Gt(ROSA)26Sor+, Trp63tm1.1(cre)Ssig/Trp63+ (more )
Note: Conditional mutant. Double labeled: red - Trp63; green - Cre reporter.
Structure Level Pattern Image Note
TS28: prostate gland Present S7B
Specimen S8B 12.5: embryonic day 12.5 (more )
Note: Triple labeled: red - Trp63; gray - Krt8 (assay MGI:7431440); green - Krt5 (assay MGI:7431454).
Structure Level Pattern Image Note
TS20: hindgut epithelium Present Regionally restricted S8B 12.5 merge , S8B p63 12.5 Expression is in the distal hindgut.
Specimen S8B 13.5: embryonic day 13.5 (more )
Note: Triple labeled: red - Trp63; gray - Krt8 (assay MGI:7431440); green - Krt5 (assay MGI:7431454).
Structure Level Pattern Image Note
TS21: hindgut Present S8B p63 13.5 , S8B 13.5 merge
Specimen S8B 15.5: embryonic day 15.5 (more )
Note: Triple labeled: red - Trp63; gray - Krt8 (assay MGI:7431440); green - Krt5 (assay MGI:7431454).
Structure Level Pattern Image Note
TS23: hindgut Present Regionally restricted S8B p63 15.5 , S8B 15.5 merge Expression is distal.
Specimen S8B 7w: postnatal week 7 (more )
Note: Triple labeled: red - Trp63; gray - Krt8 (assay MGI:7431440); green - Krt5 (assay MGI:7431454).
Structure Level Pattern Image Note
TS28: anal canal epithelium Present Regionally restricted S8B 7w merge , S8B p63 7w Expression is in the stratified epithelium of the anal-canal in basal and suprabasal cell layers.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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04/23/2024
MGI 6.23 		The Jackson Laboratory