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Gene Expression Data
Assay Details
Assay
Reference: J:197339 Pignon JC, et al., p63-expressing cells are the stem cells of developing prostate, bladder, and colorectal epithelia. Proc Natl Acad Sci U S A. 2013 May 14;110(20):8105-10
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7431440
Gene symbol: Krt8
Gene name: keratin 8
Antibody: TROMA 1
Detection system: Secondary antibody
Results
Specimen 4D: postnatal week 7; Gt(ROSA)26Sortm1(EYFP)Cos/Gt(ROSA)26Sor+, Trp63tm1.1(cre)Ssig/Trp63+ (more )
Note: Conditional mutant. Triple labeled: white - Krt8; red - Trp63 (assay MGI:7431428); green - Cre reporter.
Structure Level Pattern Image Note
TS28: prostate gland Present Regionally restricted 4D Merge , 4D CK8 , 4D Expression is in luminal cells.
Specimen S6A: embryonic day 13.5 (more )
Note: Triple labeled: gray - Krt8; red - Trp63 (assay MGI:7431428); green - Krt5 (assay MGI:7431454).
Structure Level Pattern Image Note
TS21: epithelium of urogenital sinus Present Uniform S6A CK8 , S6A Merge
Specimen S6B: embryonic day 15.5 (more )
Note: Triple labeled: gray - Krt8; red - Trp63 (assay MGI:7431428); green - Krt5 (assay MGI:7431454).
Structure Level Pattern Image Note
TS23: epithelium of urogenital sinus Present Regionally restricted S6B Merge , S6B CK8 Expression is in basal and suprabasal cells.
Specimen S6C: postnatal day 0-1 (more )
Note: Triple labeled: gray - Krt8; red - Trp63 (assay MGI:7431428); green - Krt5 (assay MGI:7431454).
Structure Level Pattern Image Note
TS27: prostate bud Present Regionally restricted S6C Merge , S6C CK8 Expression is in the proximal tips and is weak in the distal tips.
Specimen S6D: postnatal week 7 (more )
Note: Triple labeled: gray - Krt8; red - Trp63 (assay MGI:7431428); green - Krt5 (assay MGI:7431454).
Structure Level Pattern Image Note
TS28: prostate gland Present Regionally restricted S6D Merge , S6D CK8 Expression is in prostate basal cells.
Specimen S8B 12.5: embryonic day 12.5 (more )
Note: Triple labeled: gray - Krt8; red - Trp63 (assay MGI:7431428); green - Krt5 (assay MGI:7431454).
Structure Level Pattern Image Note
TS20: hindgut epithelium Present Regionally restricted S8B 12.5 merge , S8B CK8 12.5 Expression is in the distal hindgut.
Specimen S8B 13.5: embryonic day 13.5 (more )
Note: Triple labeled: gray - Krt8; red - Trp63 (assay MGI:7431428); green - Krt5 (assay MGI:7431454).
Structure Level Pattern Image Note
TS21: hindgut epithelium Present Regionally restricted S8B 13.5 merge , S8B CK8 13.5 Expression is in the distal hindgut.
Specimen S8B 15.5: embryonic day 15.5 (more )
Note: Triple labeled: gray - Krt8; red - Trp63 (assay MGI:7431428); green - Krt5 (assay MGI:7431454).
Structure Level Pattern Image Note
TS23: hindgut epithelium Present Regionally restricted S8B CK8 15.5 , S8B 15.5 merge Expression is in the distal hindgut.
Specimen S8B pw7: postnatal week 7 (more )
Note: Triple labeled: gray - Krt8; red - Trp63 (assay MGI:7431428); green - Krt5 (assay MGI:7431454).
Structure Level Pattern Image Note
TS28: colon epithelium Present Regionally restricted S8B CK8 7w , S8B 7w merge Expression is in the glandular epithelium.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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05/07/2024
MGI 6.23 		The Jackson Laboratory