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Gene Expression Data
Assay Details
Assay
Reference: J:321982 De A, et al., The beta8 integrin cytoplasmic domain activates extracellular matrix adhesion to promote brain neurovascular development. Development. 2022 Mar 15;149(6):dev200472
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7281836
Gene symbol: Aif1
Gene name: allograft inflammatory factor 1
Antibody: anti-Iba1 (019-19741)
Assay notes: The antibody used in this assay was not specified; two antibodies were listed: MGI:5620494 and MGI:7281799.
Results
Specimen 7C: postnatal month 7; Tg(Nes-cre)1Kln/0 (more )
Note: Triple labeled: blue - Aif1; red - Pecam1 (assay MGI:7281812); green - Gfap (assay MGI:7281838).
Structure Cell Type Level Pattern Image Note
TS28: cerebral cortex microglial cell Present 7C lower panels
Specimen 7D: postnatal month 7; Tg(Nes-cre)1Kln/0 (more )
Note: Triple labeled: blue - Aif1; red - Pecam1 (assay MGI:7281812); green - Gfap (assay MGI:7281838).
Structure Cell Type Level Pattern Image Note
TS28: thalamus microglial cell Present 7D lower panels
Specimen 7E: postnatal month 7; Tg(Nes-cre)1Kln/0 (more )
Note: Triple labeled: blue - Aif1; red - Pecam1 (assay MGI:7281812); green - Gfap (assay MGI:7281838).
Structure Cell Type Level Pattern Image Note
TS28: cerebellum microglial cell Present 7E lower panels
Specimen 7F: postnatal month 7; Itgb8tm2Lfr/Itgb8+, Tg(Nes-cre)1Kln/0 (more )
Note: Conditional mutant. Triple labeled: blue - Aif1; red - Pecam1 (assay MGI:7281812); green - Gfap (assay MGI:7281838).
Structure Cell Type Level Pattern Image Note
TS28: cerebral cortex microglial cell Present 7F lower panels No differences were noted in the mutant.
Specimen 7G: postnatal month 7; Itgb8tm2Lfr/Itgb8+, Tg(Nes-cre)1Kln/0 (more )
Note: Conditional mutant. Triple labeled: blue - Aif1; red - Pecam1 (assay MGI:7281812); green - Gfap (assay MGI:7281838).
Structure Cell Type Level Pattern Image Note
TS28: thalamus microglial cell Present 7G lower panels No differences were noted in the mutant.
Specimen 7H: postnatal month 7; Itgb8tm2Lfr/Itgb8+, Tg(Nes-cre)1Kln/0 (more )
Note: Conditional mutant. Triple labeled: blue - Aif1; red - Pecam1 (assay MGI:7281812); green - Gfap (assay MGI:7281838).
Structure Cell Type Level Pattern Image Note
TS28: cerebellum microglial cell Present 7H lower panels No differences were noted in the mutant.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory