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Gene Expression Data
Assay Details
Assay
Reference: J:158122 Takano-Maruyama M, et al., Placodal sensory ganglia coordinate the formation of the cranial visceral motor pathway. Dev Dyn. 2010 Apr;239(4):1155-61
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6393305
Gene symbol: Phox2b
Gene name: paired-like homeobox 2b
Antibody: anti-Phox2b
Results
Specimen 2A: embryonic day 12.5; Gt(ROSA)26Sortm1(EYFP)Cos/Gt(ROSA)26Sor+, Hoxb1tm6(cre)Mrc/Hoxb1+ (more )
Note: Conditional mutant. Double labeled: red - Phox2b; green - Cre reporter.
Structure Level Pattern Image Note
TS20: sphenopalatine ganglion Present 2A
Specimen 2B: embryonic day 12.5; Gt(ROSA)26Sortm1(EYFP)Cos/Gt(ROSA)26Sor+, Hoxb1tm6(cre)Mrc/Hoxb1+ (more )
Note: Conditional mutant. Double labeled: red - Phox2b; green - Cre reporter.
Structure Level Pattern Image Note
TS20: submandibular ganglion Present 2B
Specimen 2E: embryonic day 9.5; Gt(ROSA)26Sortm1(EYFP)Cos/Gt(ROSA)26Sor+, Hoxb1tm6(cre)Mrc/Hoxb1+ (more )
Note: Conditional mutant. Triple labeled: blue - Phox2b; red - Sox10 (assay MGI:6393306); green - Cre reporter.
Structure Level Pattern Image Note
TS15: migrating neural crest Present Regionally restricted 2E Rhombomere 4-derived neural crest cells (are shown to be engaged with the geniculate ganglion (VIIg).
TS15: facio-acoustic preganglion complex Present Regionally restricted 2E Rhombomere 4-derived neural crest cells (are shown to be engaged with the geniculate ganglion (VIIg).
Specimen 2F: embryonic day 11.5; Gt(ROSA)26Sortm1(EYFP)Cos/Gt(ROSA)26Sor+, Hoxb1tm6(cre)Mrc/Hoxb1+ (more )
Note: Conditional mutant. Triple labeled: blue - Phox2b; red - Sox10 (assay MGI:6393306); green - Cre reporter.
Structure Level Pattern Image Note
TS19: migrating neural crest Present Regionally restricted 2F Expression in rhombomere 4-derived neural crest cells.
TS19: facial ganglion Present Regionally restricted 2F Parasympathetic sensory neurons in geniculate ganglion (VIIg) expresses only Phox2b.
Specimen 2G: embryonic day 11.5; Gt(ROSA)26Sortm1(EYFP)Cos/Gt(ROSA)26Sor+, Hoxb1tm6(cre)Mrc/Hoxb1+ (more )
Note: Conditional mutant. Double labeled: red - Phox2b; green - Sox10 (assay MGI:6393306).
Structure Level Pattern Image Note
TS19: migrating neural crest Present Regionally restricted 2G Expression in cells migrating rostrally just beneath nasal and oral epithelia.
Specimen 2H: embryonic day 12.5; Gt(ROSA)26Sortm1(EYFP)Cos/Gt(ROSA)26Sor+, Hoxb1tm6(cre)Mrc/Hoxb1+ (more )
Note: Conditional mutant. Triple labeled: blue - Phox2b; red - Sox10 (assay MGI:6393306); green - Cre reporter.
Structure Level Pattern Image Note
TS20: sphenopalatine ganglion Present 2H
TS20: submandibular ganglion Present 2H
Specimen 3A: embryonic day 12.5; Gt(ROSA)26Sortm1(EYFP)Cos/Gt(ROSA)26Sor+, Hoxb1tm6(cre)Mrc/Hoxb1+ (more )
Note: Conditional mutant. Double labeled: red - Phox2b; green - Cre reporter.
Structure Level Pattern Image Note
TS20: sphenopalatine ganglion Present 3A
Specimen 3B: embryonic day 12.5; Gt(ROSA)26Sortm1(EYFP)Cos/Gt(ROSA)26Sor+, Hoxb1tm6(cre)Mrc/Hoxb1+, Neurog2tm1Fgu/Neurog2tm1Fgu (more )
Note: Conditional mutant. Double labeled: red - Phox2b; green - Cre reporter.
Structure Level Pattern Image Note
TS20: submandibular ganglion Trace 3B
Specimen 3C: embryonic day 12.5; Gt(ROSA)26Sortm1(EYFP)Cos/Gt(ROSA)26Sor+, Hoxb1tm6(cre)Mrc/Hoxb1+ (more )
Note: Conditional mutant. Double labeled: red - Phox2b; green - Cre reporter.
Structure Level Pattern Image Note
TS20: sphenopalatine ganglion Present 3C
Specimen 3D: embryonic day 12.5; Gt(ROSA)26Sortm1(EYFP)Cos/Gt(ROSA)26Sor+, Hoxb1tm6(cre)Mrc/Hoxb1+, Neurog2tm1Fgu/Neurog2tm1Fgu (more )
Note: Conditional mutant. Double labeled: red - Phox2b; green - Cre reporter.
Structure Level Pattern Image Note
TS20: submandibular ganglion Trace 3D
Specimen 4D: embryonic day 12.5; Gt(ROSA)26Sortm1(EYFP)Cos/Gt(ROSA)26Sor+, Hoxb1tm6(cre)Mrc/Hoxb1+ (more )
Note: Conditional mutant. Triple labeled: blue - Phox2b; red - Isl1 (assay MGI:6393307); green - Cre reporter.
Structure Level Pattern Image Note
TS20: facial ganglion Present Regionally restricted 4D Expression in sensory neurons of geniculate ganglion.
TS20: vestibulo-cochlear ganglion Absent 4D
Specimen 4E: embryonic day 12.5; Gt(ROSA)26Sortm1(EYFP)Cos/Gt(ROSA)26Sor+, Hoxb1tm6(cre)Mrc/Hoxb1+, Neurog2tm1Fgu/Neurog2tm1Fgu (more )
Note: Conditional mutant. Triple labeled: blue - Phox2b; red - Isl1 (assay MGI:6393307); green - Cre reporter.
Structure Level Pattern Image Note
TS20: vestibulo-cochlear ganglion Absent 4E
Specimen 4F: embryonic day 12.5; Gt(ROSA)26Sortm1(EYFP)Cos/Gt(ROSA)26Sor+, Hoxb1tm6(cre)Mrc/Hoxb1+, Sox10tm1Weg/Sox10tm1Weg (more )
Note: Conditional mutant. Triple labeled: blue - Phox2b; red - Isl1 (assay MGI:6393307); green - Cre reporter.
Structure Level Pattern Image Note
TS20: facial ganglion Present Regionally restricted 4F Preganglionic neurons reached region normally occupied by the geniculate ganglion.
Specimen 4G: embryonic day 12.5; Gt(ROSA)26Sortm1(EYFP)Cos/Gt(ROSA)26Sor+, Hoxb1tm6(cre)Mrc/Hoxb1+ (more )
Note: Conditional mutant. Double labeled: red - Phox2b; green - Cre reporter.
Structure Level Pattern Image Note
TS20: submandibular ganglion Present 4G
Specimen 4H: embryonic day 12.5; Gt(ROSA)26Sortm1(EYFP)Cos/Gt(ROSA)26Sor+, Hoxb1tm6(cre)Mrc/Hoxb1+, Neurog2tm1Fgu/Neurog2tm1Fgu (more )
Note: Conditional mutant. Double labeled: red - Phox2b; green - Cre reporter.
Structure Level Pattern Image Note
TS20: submandibular ganglion Trace Single cells 4H Few expressing cells detected in mutant.
Specimen 4I: embryonic day 12.5; Gt(ROSA)26Sortm1(EYFP)Cos/Gt(ROSA)26Sor+, Hoxb1tm6(cre)Mrc/Hoxb1+, Sox10tm1Weg/Sox10tm1Weg (more )
Note: Conditional mutant. Double labeled: red - Phox2b; green - Cre reporter.
Structure Level Pattern Image Note
TS20: submandibular ganglion Absent 4I
Specimen S1A: embryonic day 12.5; Gt(ROSA)26Sortm1(EYFP)Cos/Gt(ROSA)26Sor+, Pax7tm1(cre)Mrc/Pax7+ (more )
Note: Conditional mutant. Double labeled: red - Phox2b; green - Cre reporter.
Structure Level Pattern Image Note
TS20: sphenopalatine ganglion Present S1A
Specimen S1B: embryonic day 12.5; Gt(ROSA)26Sortm1(EYFP)Cos/Gt(ROSA)26Sor+, Hoxa3tm1(cre)Moon/Hoxa3+ (more )
Note: Conditional mutant. Double labeled: red - Phox2b; green - Cre reporter.
Structure Level Pattern Image Note
TS20: sphenopalatine ganglion Present S1B
Specimen S1C: embryonic day 12.5; Gt(ROSA)26Sortm1(EYFP)Cos/Gt(ROSA)26Sor+, Pax7tm1(cre)Mrc/Pax7+ (more )
Note: Conditional mutant. Double labeled: red - Phox2b; green - Cre reporter.
Structure Level Pattern Image Note
TS20: submandibular ganglion Present S1C
Specimen S1D: embryonic day 12.5; Gt(ROSA)26Sortm1(EYFP)Cos/Gt(ROSA)26Sor+, Hoxa3tm1(cre)Moon/Hoxa3+ (more )
Note: Conditional mutant. Double labeled: red - Phox2b; green - Cre reporter.
Structure Level Pattern Image Note
TS20: submandibular ganglion Present S1D
Specimen S2A: embryonic day 12.5; Gt(ROSA)26Sortm1(EYFP)Cos/Gt(ROSA)26Sor+, Hoxb1tm6(cre)Mrc/Hoxb1+ (more )
Note: Conditional mutant. Double labeled: red - Phox2b; green - BrdU.
Structure Level Pattern Image Note
TS20: sphenopalatine ganglion Present S2A
Specimen S2B: embryonic day 12.5; Gt(ROSA)26Sortm1(EYFP)Cos/Gt(ROSA)26Sor+, Hoxb1tm6(cre)Mrc/Hoxb1+, Neurog2tm1Fgu/Neurog2tm1Fgu (more )
Note: Conditional mutant. Double labeled: red - Phox2b; green - BrdU.
Structure Level Pattern Image Note
TS20: sphenopalatine ganglion Trace S2B
Specimen S2C: embryonic day 12.5; Gt(ROSA)26Sortm1(EYFP)Cos/Gt(ROSA)26Sor+, Hoxb1tm6(cre)Mrc/Hoxb1+ (more )
Note: Conditional mutant. Double labeled: red - Phox2b; green - BrdU.
Structure Level Pattern Image Note
TS20: submandibular ganglion Present S2C
Specimen S2D: embryonic day 12.5; Gt(ROSA)26Sortm1(EYFP)Cos/Gt(ROSA)26Sor+, Hoxb1tm6(cre)Mrc/Hoxb1+, Neurog2tm1Fgu/Neurog2tm1Fgu (more )
Note: Conditional mutant. Double labeled: red - Phox2b; green - BrdU.
Structure Level Pattern Image Note
TS20: submandibular ganglion Trace S2D
Specimen S3A: embryonic day 12.5; Gt(ROSA)26Sortm1(EYFP)Cos/Gt(ROSA)26Sor+, Hoxb1tm6(cre)Mrc/Hoxb1+ (more )
Note: Conditional mutant. Double labeled: red - Phox2b; green - Cre reporter.
Structure Level Pattern Image Note
TS20: sphenopalatine ganglion Present S3A
Specimen S3B: embryonic day 12.5; Gt(ROSA)26Sortm1(EYFP)Cos/Gt(ROSA)26Sor+, Hoxb1tm6(cre)Mrc/Hoxb1+, Sox10tm1Weg/Sox10tm1Weg (more )
Note: Conditional mutant. Double labeled: red - Phox2b; green - Cre reporter.
Structure Level Pattern Image Note
TS20: sphenopalatine ganglion Absent S3B
Specimen S3C: embryonic day 12.5; Gt(ROSA)26Sortm1(EYFP)Cos/Gt(ROSA)26Sor+, Hoxb1tm6(cre)Mrc/Hoxb1+ (more )
Note: Conditional mutant. Double labeled: red - Phox2b; green - Cre reporter.
Structure Level Pattern Image Note
TS20: submandibular ganglion Present S3C
Specimen S3D: embryonic day 12.5; Gt(ROSA)26Sortm1(EYFP)Cos/Gt(ROSA)26Sor+, Hoxb1tm6(cre)Mrc/Hoxb1+, Sox10tm1Weg/Sox10tm1Weg (more )
Note: Conditional mutant. Double labeled: red - Phox2b; green - Cre reporter.
Structure Level Pattern Image Note
TS20: submandibular ganglion Absent S3D
Specimen S4A: embryonic day 12.5; Gt(ROSA)26Sortm1(EYFP)Cos/Gt(ROSA)26Sor+, Hoxb1tm6(cre)Mrc/Hoxb1+ (more )
Note: Conditional mutant. Double labeled: red - Phox2b; green - TUNEL.
Structure Level Pattern Image Note
TS20: sphenopalatine ganglion Present S4A
Specimen S4B: embryonic day 12.5; Gt(ROSA)26Sortm1(EYFP)Cos/Gt(ROSA)26Sor+, Hoxb1tm6(cre)Mrc/Hoxb1+, Neurog2tm1Fgu/Neurog2tm1Fgu (more )
Note: Conditional mutant. Double labeled: red - Phox2b; green - TUNEL.
Structure Level Pattern Image Note
TS20: sphenopalatine ganglion Trace S4B
Specimen S4C: embryonic day 12.5; Gt(ROSA)26Sortm1(EYFP)Cos/Gt(ROSA)26Sor+, Hoxb1tm6(cre)Mrc/Hoxb1+ (more )
Note: Conditional mutant. Double labeled: red - Phox2b; green - TUNEL.
Structure Level Pattern Image Note
TS20: submandibular ganglion Present S4C
Specimen S4D: embryonic day 12.5; Gt(ROSA)26Sortm1(EYFP)Cos/Gt(ROSA)26Sor+, Hoxb1tm6(cre)Mrc/Hoxb1+, Neurog2tm1Fgu/Neurog2tm1Fgu (more )
Note: Conditional mutant. Double labeled: red - Phox2b; green - TUNEL.
Structure Level Pattern Image Note
TS20: submandibular ganglion Trace S4D
Specimen S6A: embryonic day 12.5; Gt(ROSA)26Sortm1(EYFP)Cos/Gt(ROSA)26Sor+, Hoxb1tm6(cre)Mrc/Hoxb1+ (more )
Note: Conditional mutant. Double labeled: red - Phox2b; green - Cre reporter.
Structure Level Pattern Image Note
TS20: sphenopalatine ganglion Present S6A
Specimen S6B: embryonic day 12.5; Gt(ROSA)26Sortm1(EYFP)Cos/Gt(ROSA)26Sor+, Hoxb1tm6(cre)Mrc/Hoxb1+, Neurog2tm1Fgu/Neurog2tm1Fgu (more )
Note: Conditional mutant. Double labeled: red - Phox2b; green - Cre reporter.
Structure Level Pattern Image Note
TS20: sphenopalatine ganglion Trace S6B Authors report few, if any, expressing cells detected.
Specimen S6C: embryonic day 12.5; Gt(ROSA)26Sortm1(EYFP)Cos/Gt(ROSA)26Sor+, Hoxb1tm6(cre)Mrc/Hoxb1+, Sox10tm1Weg/Sox10tm1Weg (more )
Note: Conditional mutant. Double labeled: red - Phox2b; green - Cre reporter.
Structure Level Pattern Image Note
TS20: sphenopalatine ganglion Absent S6C Authors report few, if any, expressing cells detected.
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