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Gene Expression Data
Assay Details
Assay
Reference: J:158122 Takano-Maruyama M, et al., Placodal sensory ganglia coordinate the formation of the cranial visceral motor pathway. Dev Dyn. 2010 Apr;239(4):1155-61
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6393306
Gene symbol: Sox10
Gene name: SRY (sex determining region Y)-box 10
Antibody: anti-Sox10
Results
Specimen 2E: embryonic day 9.5; Gt(ROSA)26Sortm1(EYFP)Cos/Gt(ROSA)26Sor+, Hoxb1tm6(cre)Mrc/Hoxb1+ (more )
Note: Conditional mutant. Triple labeled: red - Sox10; blue - Phox2b (assay MGI:6393305); green - Cre reporter.
Structure Level Pattern Image Note
TS15: migrating neural crest Present 2E Rhombomere 4-derived neural crest cells (are shown to be engaged with the geniculate ganglion (VIIg).
TS15: facio-acoustic preganglion complex Present Regionally restricted 2E Rhombomere 4-derived neural crest cells (are shown to be engaged with the geniculate ganglion (VIIg).
Specimen 2F: embryonic day 11.5; Gt(ROSA)26Sortm1(EYFP)Cos/Gt(ROSA)26Sor+, Hoxb1tm6(cre)Mrc/Hoxb1+ (more )
Note: Conditional mutant. Triple labeled: red - Sox10; blue - Phox2b (assay MGI:6393305); green - Cre reporter.
Structure Level Pattern Image Note
TS19: migrating neural crest Present Regionally restricted 2F Expression in rhombomere 4-derived neural crest cells.
TS19: facial ganglion Present 2F
Specimen 2G: embryonic day 11.5; Gt(ROSA)26Sortm1(EYFP)Cos/Gt(ROSA)26Sor+, Hoxb1tm6(cre)Mrc/Hoxb1+ (more )
Note: Conditional mutant. Double labeled: green - Sox10; red - Phox2b (assay MGI:6393305).
Structure Level Pattern Image Note
TS19: migrating neural crest Present Regionally restricted 2G Expression in cells migrating rostrally just beneath nasal and oral epithelia.
Specimen 2H: embryonic day 12.5; Gt(ROSA)26Sortm1(EYFP)Cos/Gt(ROSA)26Sor+, Hoxb1tm6(cre)Mrc/Hoxb1+ (more )
Note: Conditional mutant. Triple labeled: red - Sox10; blue - Phox2b (assay MGI:6393305); green - Cre reporter.
Structure Level Pattern Image Note
TS20: sphenopalatine ganglion Present 2H
TS20: submandibular ganglion Present 2H
Specimen 3E: embryonic day 9.5; Gt(ROSA)26Sortm1(EYFP)Cos/Gt(ROSA)26Sor+, Hoxb1tm6(cre)Mrc/Hoxb1+ (more )
Note: Conditional mutant. Triple labeled: blue - Sox10; red - Isl1 (assay MGI:6393307); green - Cre reporter.
Structure Level Pattern Image Note
TS15: facio-acoustic preganglion complex Present 3E
TS15: migrating neural crest Present 3E
Specimen 3F: embryonic day 9.5; Gt(ROSA)26Sortm1(EYFP)Cos/Gt(ROSA)26Sor+, Hoxb1tm6(cre)Mrc/Hoxb1+, Neurog2tm1Fgu/Neurog2tm1Fgu (more )
Note: Conditional mutant. Triple labeled: blue - Sox10; red - Isl1 (assay MGI:6393307); green - Cre reporter.
Structure Level Pattern Image Note
TS15: facio-acoustic preganglion complex Present Regionally restricted 3F Authors report thinning rostral rhombomere 4-derived neural crest migratory stream.
TS15: migrating neural crest Weak Regionally restricted 3F Authors report thinning rostral rhombomere 4-derived neural crest migratory stream.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory