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Gene Expression Data
Assay Details
Assay
Reference: J:158122 Takano-Maruyama M, et al., Placodal sensory ganglia coordinate the formation of the cranial visceral motor pathway. Dev Dyn. 2010 Apr;239(4):1155-61
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6393307
Gene symbol: Isl1
Gene name: ISL1 transcription factor, LIM/homeodomain
Antibody: anti-Isl1
Results
Specimen 3E: embryonic day 9.5; Gt(ROSA)26Sortm1(EYFP)Cos/Gt(ROSA)26Sor+, Hoxb1tm6(cre)Mrc/Hoxb1+ (more )
Note: Conditional mutant. Triple labeled: red - Isl1; blue - Sox10 (assay MGI:6393306); green - Cre reporter.
Structure Level Pattern Image Note
TS15: facio-acoustic preganglion complex Present Regionally restricted 3E Expression in geniculate ganglion that has delaminated from surface epibranchial placode.
Specimen 3F: embryonic day 9.5; Gt(ROSA)26Sortm1(EYFP)Cos/Gt(ROSA)26Sor+, Hoxb1tm6(cre)Mrc/Hoxb1+, Neurog2tm1Fgu/Neurog2tm1Fgu (more )
Note: Conditional mutant. Triple labeled: red - Isl1; blue - Sox10 (assay MGI:6393306); green - Cre reporter.
Structure Level Pattern Image Note
TS15: facio-acoustic preganglion complex Absent 3F
Specimen 4D: embryonic day 12.5; Gt(ROSA)26Sortm1(EYFP)Cos/Gt(ROSA)26Sor+, Hoxb1tm6(cre)Mrc/Hoxb1+ (more )
Note: Conditional mutant. Triple labeled: red - Isl1; blue - Sox10 (assay MGI:6393306); green - Cre reporter.
Structure Level Pattern Image Note
TS20: facial ganglion Present 4D Expression in sensory neurons of geniculate ganglion and vesibulocochlear ganglion.
TS20: vestibulo-cochlear ganglion Present 4D Expression in sensory neurons of geniculate ganglion and vesibulocochlear ganglion.
Specimen 4E: embryonic day 12.5; Gt(ROSA)26Sortm1(EYFP)Cos/Gt(ROSA)26Sor+, Hoxb1tm6(cre)Mrc/Hoxb1+, Neurog2tm1Fgu/Neurog2tm1Fgu (more )
Note: Conditional mutant. Triple labeled: red - Isl1; blue - Sox10 (assay MGI:6393306); green - Cre reporter.
Structure Level Pattern Image Note
TS20: facial ganglion Absent 4E Preganglionic axons failed to extend into normally occupied by the geniculate ganglion.
TS20: vestibulo-cochlear ganglion Present 4E
Specimen 4F: embryonic day 12.5; Gt(ROSA)26Sortm1(EYFP)Cos/Gt(ROSA)26Sor+, Hoxb1tm6(cre)Mrc/Hoxb1+, Sox10tm1Weg/Sox10tm1Weg (more )
Note: Conditional mutant. Triple labeled: red - Isl1; blue - Sox10 (assay MGI:6393306); green - Cre reporter.
Structure Level Pattern Image Note
TS20: facial ganglion Present 4F Preganglionic neurons reached region normally occupied by the geniculate ganglion.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory