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Gene Expression Data
Assay Details
Assay
Reference: J:245736 Nakagawa S, et al., Malat1 is not an essential component of nuclear speckles in mice. RNA. 2012 Aug;18(8):1487-99
Assay type: RNA in situ
MGI Accession ID: MGI:6197085
Gene symbol: Malat1
Gene name: metastasis associated lung adenocarcinoma transcript 1 (non-coding RNA)
Results
Specimen 4C Kidney WT: postnatal adult (more )
Note: Double labeled: white - Malat1; pink - Srsf1 (assay MGI:6197098).
Structure Level Pattern Image Note
TS28: metanephros Present Spotted 4C Kidney WT Malat1 , 4C Kidney WT merge Authors report expression in speckles.
Specimen 4C Kidney KO: postnatal adult; Malat1tm1.1Shna/Malat1tm1.1Shna (more )
Note: Double labeled: white - Malat1; pink - Srsf1 (assay MGI:6197098).
Structure Level Pattern Image Note
TS28: metanephros Absent 4C Kidney KO Malat1 , 4C Kidney KO merge
Specimen 4C Stomach WT: postnatal adult (more )
Note: Double labeled: white - Malat1; pink - Srsf1 (assay MGI:6197098).
Structure Level Pattern Image Note
TS28: stomach Present Spotted 4C Stomach WT Malat1 , 4C Stomach WT merge Authors report expression in speckles.
Specimen 4C Stomach KO: postnatal adult; Malat1tm1.1Shna/Malat1tm1.1Shna (more )
Note: Double labeled: white - Malat1; pink - Srsf1 (assay MGI:6197098).
Structure Level Pattern Image Note
TS28: stomach Absent 4C Stomach KO merge , 4C Stomach KO Malat1
Specimen 4C Hippocampus DG WT: postnatal adult (more )
Note: Double labeled: white - Malat1; pink - Srsf1 (assay MGI:6197098).
Structure Level Pattern Image Note
TS28: dentate gyrus Present Spotted 4C DG WT Malat1 , 4C DG WT merge Authors report expression in speckles.
Specimen 4C Hippocampus DG KO: postnatal adult; Malat1tm1.1Shna/Malat1tm1.1Shna (more )
Note: Double labeled: white - Malat1; pink - Srsf1 (assay MGI:6197098).
Structure Level Pattern Image Note
TS28: dentate gyrus Absent 4C DG KO Malat1 , 4C DG KO merge
Specimen 4C Liver WT: postnatal adult (more )
Note: Double labeled: white - Malat1; pink - Srsf1 (assay MGI:6197098).
Structure Level Pattern Image Note
TS28: liver Present Spotted 4C Liver WT Malat1 , 4C Liver WT merge Authors report expression in speckles.
Specimen 4C Liver KO: postnatal adult; Malat1tm1.1Shna/Malat1tm1.1Shna (more )
Note: Double labeled: white - Malat1; pink - Srsf1 (assay MGI:6197098).
Structure Level Pattern Image Note
TS28: liver Absent 4C Liver KO merge , 4C Liver KO Malat1
Specimen 4D Cerebral cortex WT short exp.: postnatal adult (more )
Note: Double labeled: white - Malat1; pink - Srsf1 (assay MGI:6197098).
Structure Level Pattern Image Note
TS28: cerebral cortex Present Spotted 4D WT Malat1 short exp. Authors report expression in speckles.
Specimen 4D Cerebral cortex WT long exp.: postnatal adult (more )
Note: Double labeled: white - Malat1; pink - Srsf1 (assay MGI:6197098).
Structure Level Pattern Image Note
TS28: cerebral cortex Present Spotted 4D WT merge , 4D WT Malat1 long exp.
Specimen 4D Cerebral cortex KO short exp.: postnatal adult; Malat1tm1.1Shna/Malat1tm1.1Shna (more )
Note: Double labeled: white - Malat1; pink - Srsf1 (assay MGI:6197098).
Structure Level Pattern Image Note
TS28: cerebral cortex Ambiguous 4D KO Malat1 short exp.
Specimen 4D Cerebral cortex KO long exp.: postnatal adult; Malat1tm1.1Shna/Malat1tm1.1Shna (more )
Note: Double labeled: white - Malat1; pink - Srsf1 (assay MGI:6197098).
Structure Level Pattern Image Note
TS28: cerebral cortex Weak Spotted 4D KO merge , 4D KO Malat1 long exp. Authors report residual expression in cerebral cortex - the short form of Malat1 localized to nuclear speckles.
Specimen 5A low magnification: postnatal adult (more )
Structure Level Pattern Image Note
TS28: colon Strong Regionally restricted 5A low mag. Malat1 Higher levels of expression in colonic surface epithelial cells facing lumen.
Specimen 5A higher magnification: postnatal adult (more )
Structure Level Pattern Image Note
TS28: colon Strong Regionally restricted 5A higher mag. Malat1
Specimen 7B WT (left): postnatal adult (more )
Note: Double labeled: green - Malat1; pink - Neat1 (assay MGI:6197087).
Structure Level Pattern Image Note
TS28: intestine Present 7B WT Malat1 (left) , 7B WT merge (left)
Specimen 7B KO (left): postnatal adult; Malat1tm1.1Shna/Malat1tm1.1Shna (more )
Note: Double labeled: green - Malat1; pink - Neat1 (assay MGI:6197087).
Structure Level Pattern Image Note
TS28: intestine Absent 7B KO Malat1 (left) , 7B KO merge (left)
Specimen 7B WT (right): postnatal adult (more )
Note: Double labeled: green - Malat1; pink - Neat1 (assay MGI:6197087).
Structure Level Pattern Image Note
TS28: intestine Present 7B WT Malat1 (right) , 7B WT merge (right)
Specimen 7B KO (right): postnatal adult; Malat1tm1.1Shna/Malat1tm1.1Shna (more )
Note: Double labeled: green - Malat1; pink - Neat1 (assay MGI:6197087).
Structure Level Pattern Image Note
TS28: intestine Absent 7B KO merge (right) , 7B KO Malat1 (right)
Specimen 7C WT (left): postnatal adult (more )
Note: Double labeled: green - Malat1; pink - Sfpq (assay MGI:6197099).
Structure Level Pattern Image Note
TS28: stomach proventricular region Present 7C WT Malat1 (left) , 7C WT merge (left)
Specimen 7C KO (left): postnatal adult; Malat1tm1.1Shna/Malat1tm1.1Shna (more )
Note: Double labeled: green - Malat1; pink - Sfpq (assay MGI:6197099).
Structure Level Pattern Image Note
TS28: stomach proventricular region Absent 7C KO Malat1 (left) , 7C KO merge (left)
Specimen 7C WT (right): postnatal adult (more )
Note: Double labeled: green - Malat1; pink - Sfpq (assay MGI:6197099).
Structure Level Pattern Image Note
TS28: stomach proventricular region Present 7C WT Malat1 (right) , 7C WT merge (right)
Specimen 7C KO (right): postnatal adult; Malat1tm1.1Shna/Malat1tm1.1Shna (more )
Note: Double labeled: green - Malat1; pink - Sfpq (assay MGI:6197099).
Structure Level Pattern Image Note
TS28: stomach proventricular region Absent 7C KO merge (right) , 7C KO Malat1 (right)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory