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Gene Expression Data
Assay Details
Assay
Reference: J:245736 Nakagawa S, et al., Malat1 is not an essential component of nuclear speckles in mice. RNA. 2012 Aug;18(8):1487-99
Assay type: RNA in situ
MGI Accession ID: MGI:6197087
Gene symbol: Neat1
Gene name: nuclear paraspeckle assembly transcript 1 (non-protein coding)
Results
Specimen 5A low magnification: postnatal adult (more )
Structure Level Pattern Image Note
TS28: colon Present Regionally restricted 5A low mag. Neat1_2 Expression specifically in colonic surface epithelial cells facing the lumen.
Specimen 5A higher magnification: postnatal adult (more )
Structure Level Pattern Image Note
TS28: colon Present Regionally restricted 5A higher mag. Neat1_2 Expression in nuclear bodies known as paraspeckles.
Specimen 7B WT: postnatal adult (more )
Note: Double labeled: pink - Neat1; green - Malat1 (assay MGI:6197085).
Structure Level Pattern Image Note
TS28: intestine Present 7B WT NEAT1_2 , 7B WT merge (left)
Specimen 7B KO: postnatal adult; Malat1tm1.1Shna/Malat1tm1.1Shna (more )
Note: Double labeled: pink - Neat1; green - Malat1 (assay MGI:6197085).
Structure Level Pattern Image Note
TS28: intestine Weak Regionally restricted 7B KO NEAT1_2 , 7B KO merge (left) Authors report decreased formation of paraspeckles in KO mice.
Specimen 7C WT: postnatal adult (more )
Note: Double labeled: pink - Neat1; green - Malat1 (assay MGI:6197085).
Structure Level Pattern Image Note
TS28: stomach proventricular region Present 7C WT merge (left) , 7C WT NEAT1_2
Specimen 7C kO: postnatal adult; Malat1tm1.1Shna/Malat1tm1.1Shna (more )
Note: Double labeled: pink - Neat1; green - Malat1 (assay MGI:6197085).
Structure Level Pattern Image Note
TS28: stomach proventricular region Present 7C KO merge (left) , 7C KO NEAT1_2 Authors report other tissues including forestomach formed distinct paraspeckles.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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05/21/2024
MGI 6.23 		The Jackson Laboratory