Malat1^tm1.1Shna
Targeted Allele Detail

Summary

• Symbol: Malat1^tm1.1Shna
• Name: metastasis associated lung adenocarcinoma transcript 1 (non-coding RNA); targeted mutation 1.1, Shinichi Nakagawa
• MGI ID: MGI:6149750
• Synonyms: Malat1^lacZ
• Gene: Malat1 Location: Chr19:5845718-5852700 bp, - strand Genetic Position: Chr19, 4.34 cM
• Alliance: Malat1^tm1.1Shna page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:245736
• Parent Cell Line: TT2 (ES Cell)
• Strain of Origin: (C57BL/6NCrlj x CBA/JNCrlj)F1

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutations: Insertion, Intragenic deletion
• Mutation details: LacZ and polyadenylation signals were inserted 69 bp downstream from the transcription start site. An adjacent frt-flanked neomycin selection cassette was removed via FLP-mediated recombination. (J:245736)

Expression

In Mice Carrying this Mutation:

54 assay results 1 RNA-Seq or microarray experiment(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Malat1 Mutation: 8 strains or lines available

References

• Original: J:245736 Nakagawa S, et al., Malat1 is not an essential component of nuclear speckles in mice. RNA. 2012 Aug;18(8):1487-99
• All: 7 reference(s)