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Mir27a Gene Detail
Summary
  • Symbol
    Mir27a
  • Name
    microRNA 27a
  • Synonyms
    Mirn27a, mmu-mir-27a
Location &
Maps
more
  • Sequence Map
    Chr8:84935301-84935387 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 8, 40.58 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    34 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2676902
 miRNA gene Chr8:84935301-84935387 (+)
129S1/SvImJ MGP_129S1SvImJ_G0009125
 miRNA gene Chr8:85084353-85084439 (+)
A/J MGP_AJ_G0009106
 miRNA gene Chr8:81753109-81753195 (+)
AKR/J MGP_AKRJ_G0009097
 miRNA gene Chr8:84170933-84171019 (+)
BALB/cJ MGP_BALBcJ_G0009091
 miRNA gene Chr8:81858681-81858767 (+)
C3H/HeJ MGP_C3HHeJ_G0009030
 miRNA gene Chr8:84779111-84779197 (+)
C57BL/6NJ MGP_C57BL6NJ_G0009331
 miRNA gene Chr8:88352102-88352188 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0008200
 miRNA gene Chr8:75549335-75549421 (+)
CAST/EiJ MGP_CASTEiJ_G0008865
 miRNA gene Chr8:84204797-84204883 (+)
CBA/J MGP_CBAJ_G0008999
 miRNA gene Chr8:91451862-91451948 (+)
DBA/2J MGP_DBA2J_G0009029
 miRNA gene Chr8:81390433-81390519 (+)
FVB/NJ MGP_FVBNJ_G0009047
 miRNA gene Chr8:80321082-80321168 (+)
LP/J MGP_LPJ_G0009125
 miRNA gene Chr8:85198166-85198252 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0009012
 miRNA gene Chr8:93962774-93962860 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0009302
 miRNA gene Chr8:84149218-84149304 (+)
PWK/PhJ MGP_PWKPhJ_G0008792
 miRNA gene Chr8:80616943-80617029 (+)
SPRET/EiJ MGP_SPRETEiJ_G0008634
 miRNA gene Chr8:82965784-82965870 (+)
WSB/EiJ MGP_WSBEiJ_G0008960
 miRNA gene Chr8:84556910-84556996 (+)



Homology
more
  • Human Ortholog
    MIR27A, microRNA 27a
  • Vertebrate Orthologs
    1
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    MIR27A, microRNA 27a
  • Synonyms
    MIR27, mir-27a, MIRN27A
  • Links
    NCBI Gene ID: 407018

  • Chr Location
    chr19:13836440-13836517 (-)  GRCh38
Human Diseases
more
  • Diseases
    1 with human MIR27A associations

Human Disease Mouse Models
      
IDs
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    36 phenotype references
  • All Mutations and Alleles
    6
  • Chemically induced (other)
    1
  • Endonuclease-mediated
    2
  • Radiation induced
    1
  • Targeted
    2
  • Genomic Mutations
    4 involving Mir27a
  • Find Mice (IMSR)
    2 strains or lines available
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    11
  • GO References
    7
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    721
  • Tissues
    14
  • Literature Summary
    10
Sequences &
Gene Models
less
  • All Sequences
    24
  • RefSeq
    1
Representative SequencesLengthStrain/SpeciesFlank
genomic 387220 NCBI Gene Model | MGI Sequence Detail 87 C57BL/6J ±  kb
transcript NR_029746 RefSeq | MGI Sequence Detail 87 C57BL/6  
For the selected sequence
Molecular
Reagents
less
  • All nucleic 5
    Primer pair 3
    Other 2
Other Database
Links
less
miRBase MI0000578
References
more
  • Summaries
    All 80
    Developmental Gene Expression 10
    Gene Ontology 7
    Phenotypes 36
  • Earliest
    J:13049 Gruneberg H, Genetical studies on the skeleton of the mouse. XVIII. Three genes for syndactylism. J Genet. 1956;54(1):113-145
  • Latest
    J:345025 Wang S, et al., miRNA-27a is essential for bone remodeling by modulating p62-mediated osteoclast signaling. Elife. 2023 Feb 8;12
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
04/16/2024
MGI 6.23 		The Jackson Laboratory