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Mirc11 Complex/Cluster/Region Detail
Summary
  • Symbol
    Mirc11
  • Name
    microRNA cluster 11, including Mir23a through Mir24-2
  • Feature Type
    complex/cluster/region
  • IDs
    MGI:5295773
  • Cluster Members
    Mir23a, Mir27a, Mir24-2 ... (4 members)
Location &
Maps
more
  • Sequence Map
    Chr8:84935147-84935550 bp
    From MGI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 8, Syntenic
Strain
Comparison
more
  • SNPs within 2kb
    38 from dbSNP Build 142
Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    14 phenotypes from 1 allele in 1 genetic background
    1 phenotype from multigenic genotypes
    8 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice homozygous for a knock-out allele exhibit enhanced B cell lymphogenesis and impaired myelopoiesis.
Other Database
Links
less
miRBase MI0000571, MI0000572, MI0000578, MI0014104
References
more
  • Summaries
    All 11
    Phenotypes 8
  • Earliest
    J:105741 Griffiths-Jones S, et al., miRBase: microRNA sequences, targets and gene nomenclature. Nucleic Acids Res. 2006 Jan 1;34(Database issue):D140-4
  • Latest
    J:344664 Sprenkle NT, et al., The miR-23-27-24 clusters drive lipid-associated macrophage proliferation in obese adipose tissue. Cell Rep. 2023 Aug 29;42(8):112928
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
04/09/2024
MGI 6.23 		The Jackson Laboratory