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Rab39b Gene Detail
Summary
  • Symbol
    Rab39b
  • Name
    RAB39B, member RAS oncogene family
  • Synonyms
    6330580M05Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1915040
    NCBI Gene: 67790
  • Alliance
    genome feature page
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    ChrX:74615652-74621837 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome X, 38.26 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    107 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1915040
 protein coding gene ChrX:74615651-74621837 (-)
129S1/SvImJ ENSMUSG00200040659
 protein coding gene ChrX:56630865-56637055 (-)
A/J ENSMUSG00195031308
 protein coding gene ChrX:60356542-60362727 (-)
AKR/J ENSMUSG00220046471
 protein coding gene ChrX:55510900-55517085 (-)
BALB/cJ ENSMUSG00180049361
 protein coding gene ChrX:56931274-56937459 (-)
C3H/HeJ ENSMUSG00175034465
 protein coding gene ChrX:60521758-60527943 (-)
C57BL/6NJ ENSMUSG00215039719
 protein coding gene ChrX:57017256-57023441 (-)
CAROLI/EiJ no annotation
CAST/EiJ ENSTCUG00005038219
 protein coding gene ChrX:58397759-58403946 (-)
CBA/J ENSMUSG00210041262
 protein coding gene ChrX:57201559-57207744 (-)
DBA/2J ENSMUSG00185032060
 protein coding gene ChrX:69623301-69629486 (-)
FVB/NJ ENSMUSG00205030379
 protein coding gene ChrX:56489001-56495191 (-)
JF1/MsJ ENSUMUG00000037598
 protein coding gene ChrX:90450845-90457034 (-)
LP/J ENSMUSG00230031535
 protein coding gene ChrX:76189433-76195623 (-)
NOD/ShiLtJ ENSMUSG00190039012
 protein coding gene ChrX:56441348-56447538 (-)
NZO/HlLtJ ENSMUSG00225046944
 protein coding gene ChrX:81406605-81412790 (-)
PWK/PhJ ENSLUMG00010042775
 protein coding gene ChrX:56071807-56077996 (-)
SPRET/EiJ ENSMSPG00010028601
 protein coding gene ChrX:59505493-59511675 (-)
WSB/EiJ ENSIUOG00005045187
 protein coding gene ChrX:57200098-57206284 (-)



Homology
more
  • Human Ortholog
    RAB39B, RAB39B, member RAS oncogene family
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    RAB39B, RAB39B, member RAS oncogene family
  • Synonyms
    BGMR, MRX72, WSMN, WSN, XLID72
  • Links
    NCBI Gene ID: 116442
    UniProt: Q96DA2

  • Chr Location
    Xq28; chrX:155258235-155264491 (-)  GRCh38
Human Diseases
more
  • Diseases
    2 with Rab39b mouse models; 2 with human RAB39B associations

Human Disease Mouse Models
      
IDs
 View 1 model
      
IDs
 View 1 model
      
IDs
Click on a disease name to see all genes associated with that disease.

  • Mutations/Alleles
    2 with disease annotations
  • References
    2 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    29 phenotypes from 3 alleles in 3 genetic backgrounds
    9 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Homozygous knockout in females results in increased brain size and decreased body weight and, in hemizygous KO in males, social memory and motor learning deficits.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    37
  • GO References
    12
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    641
  • Tissues
    12
  • cDNA Data
    20
  • Literature Summary
    5
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000031202 Ensembl Gene Model | MGI Sequence Detail 6186 C57BL/6J ±  kb
    transcript ENSMUST00000033545 Ensembl | MGI Sequence Detail 3401 Not Applicable  
    polypeptide ENSMUSP00000033545 Ensembl | MGI Sequence Detail 213 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 23
      cDNA 20
      Primer pair 2
      Other 1

      Microarray probesets 4
    References
    more
    • Summaries
      All 46
      Developmental Gene Expression 5
      Diseases 2
      Gene Ontology 12
      Phenotypes 9
    • Earliest
      J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
    • Latest
      J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    09/08/2026
    MGI 6.24     		The Jackson Laboratory