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Aste1 Gene Detail
Summary
  • Symbol
    Aste1
  • Name
    asteroid homolog 1
  • Synonyms
    1100001A21Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1913845
    NCBI Gene: 66595
  • Alliance
    gene page
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    Chr9:105272533-105285497 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 9, 56.61 cM, cytoband F1
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    143 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1913845
 protein coding gene Chr9:105272533-105289428 (+)
129S1/SvImJ MGP_129S1SvImJ_G0035214
 protein coding gene Chr9:107130269-107145414 (+)
A/J MGP_AJ_G0035194
 protein coding gene Chr9:103257609-103272742 (+)
AKR/J MGP_AKRJ_G0035126
 protein coding gene Chr9:105846812-105861957 (+)
BALB/cJ MGP_BALBcJ_G0035187
 protein coding gene Chr9:102961468-102976602 (+)
C3H/HeJ MGP_C3HHeJ_G0034897
 protein coding gene Chr9:106246765-106261901 (+)
C57BL/6NJ MGP_C57BL6NJ_G0035707
 protein coding gene Chr9:110087866-110104692 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0032605
 protein coding gene Chr9:100785612-100802701 (+)
CAST/EiJ MGP_CASTEiJ_G0034209
 protein coding gene Chr9:106127267-106155892 (+)
CBA/J MGP_CBAJ_G0034866
 protein coding gene Chr9:113925724-113940865 (+)
DBA/2J MGP_DBA2J_G0035027
 protein coding gene Chr9:102743575-102758704 (+)
FVB/NJ MGP_FVBNJ_G0034975
 protein coding gene Chr9:101519534-101534676 (+)
LP/J MGP_LPJ_G0035103
 protein coding gene Chr9:107343660-107358801 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0035014
 protein coding gene Chr9:115633959-115649134 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0035729
 protein coding gene Chr9:106088252-106103389 (+)
PWK/PhJ MGP_PWKPhJ_G0033916
 protein coding gene Chr9:103031065-103047993 (+)
SPRET/EiJ MGP_SPRETEiJ_G0033751
 protein coding gene Chr9:106146967-106163815 (+)
WSB/EiJ MGP_WSBEiJ_G0034329
 protein coding gene Chr9:105960070-105975221 (+)



Homology
more
  • Human Ortholog
    ASTE1, asteroid homolog 1
  • Vertebrate Orthologs
    4
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    ASTE1, asteroid homolog 1
  • Synonyms
    HT001
  • Links
    NCBI Gene ID: 28990
    neXtProt AC: NX_Q2TB18
    UniProt: Q2TB18

  • Chr Location
    3q22.1; chr3:131013875-131027649 (-)  GRCh38
Human Diseases
more
  • Diseases
    2 with human ASTE1 associations

Human Disease Mouse Models
      
IDs
IDs
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    2 phenotypes from 1 allele in 1 genetic background
    6 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

No experimental evidence to support Biological Process annotation, following literature review. See J:73796.
Cellular Component

No experimental evidence to support Cellular Component annotation, following literature review. See J:73796.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    709
  • Tissues
    3
  • cDNA Data
    29
  • Literature Summary
    1
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 66595 NCBI Gene Model | MGI Sequence Detail 12965 C57BL/6J ±  kb
transcript NR_152139 RefSeq | MGI Sequence Detail 2844 C57BL/6  
polypeptide Q8BIR2 UniProt | EBI | MGI Sequence Detail 672 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 31
    cDNA 29
    Primer pair 1
    Other 1

    Microarray probesets 3
Other
Accession IDs
less
MGI:2143248
References
more
  • Summaries
    All 30
    Developmental Gene Expression 1
    Phenotypes 6
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:325306 Zhao F, et al., ASTE1 promotes shieldin-complex-mediated DNA repair by attenuating end resection. Nat Cell Biol. 2021 Aug;23(8):894-904
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
04/16/2024
MGI 6.23 		The Jackson Laboratory