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Isoc1 Gene Detail
Summary
  • Symbol
    Isoc1
  • Name
    isochorismatase domain containing 1
  • Synonyms
    2610034N03Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1913557
    NCBI Gene: 66307
  • Alliance
    genome feature page
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    Chr18:58792554-58812642 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 18, 33.71 cM, cytoband D2
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    780 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1913557
 protein coding gene Chr18:58792538-58813440 (+)
129S1/SvImJ ENSMUSG00200032523
 protein coding gene Chr18:55888638-55909513 (+)
A/J ENSMUSG00195005100
 protein coding gene Chr18:56016099-56037106 (+)
AKR/J ENSMUSG00220015903
 protein coding gene Chr18:55997734-56018647 (+)
BALB/cJ ENSMUSG00180012227
 protein coding gene Chr18:56587535-56608541 (+)
C3H/HeJ ENSMUSG00175034729
 protein coding gene Chr18:56199321-56220224 (+)
C57BL/6NJ ENSMUSG00215037603
 protein coding gene Chr18:55522139-55543042 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0022298
 protein coding gene Chr18:55422826-55442684 (+)
CAST/EiJ ENSTCUG00005026533
 protein coding gene Chr18:55396123-55416806 (+)
CBA/J ENSMUSG00210028860
 protein coding gene Chr18:56151826-56172830 (+)
DBA/2J ENSMUSG00185015496
 protein coding gene Chr18:56051463-56072365 (+)
FVB/NJ ENSMUSG00205017056
 protein coding gene Chr18:55510859-55531742 (+)
JF1/MsJ ENSUMUG00000029565
 protein coding gene Chr18:55920777-55941045 (+)
LP/J ENSMUSG00230011349
 protein coding gene Chr18:58063554-58084551 (+)
NOD/ShiLtJ ENSMUSG00190029804
 protein coding gene Chr18:55784526-55805406 (+)
NZO/HlLtJ ENSMUSG00225034542
 protein coding gene Chr18:57925488-57945863 (+)
PWK/PhJ ENSLUMG00010008421
 protein coding gene Chr18:56069428-56089714 (+)
SPRET/EiJ ENSMSPG00010017759
 protein coding gene Chr18:56488086-56506593 (+)
WSB/EiJ ENSIUOG00005008471
 protein coding gene Chr18:55683906-55704321 (+)



Homology
more
  • Human Ortholog
    ISOC1, isochorismatase domain containing 1
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    ISOC1, isochorismatase domain containing 1
  • Synonyms
    CGI-111
  • Links
    NCBI Gene ID: 51015
    UniProt: Q96CN7

  • Chr Location
    5q23.3; chr5:129094711-129114031 (+)  GRCh38
Human Diseases
less
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    17 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    3
  • GO References
    3
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

No experimental evidence to support Biological Process annotation, following literature review. See J:73796.
Cellular Component

Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    604
  • Tissues
    5
  • cDNA Data
    9
  • Literature Summary
    3
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 66307 NCBI Gene Model | MGI Sequence Detail 20089 C57BL/6J ±  kb
transcript NM_025478 RefSeq | MGI Sequence Detail 2563 C57BL/6  
polypeptide Q91V64 UniProt | EBI | MGI Sequence Detail 297 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    3 Sequences
  • Protein Ontology
    PR:000031796 isochorismatase domain-containing protein 1
    (term hierarchy)
  • InterPro Domains
    IPR059933 ISOC1, N-terminal ubiquitin-like domain
    IPR050993 Isochorismatase domain-containing protein
    IPR000868 Isochorismatase-like domain
    IPR036380 Isochorismatase-like superfamily
  • GlyGen
    Q91V64 1 site, 1 O-linked glycan (1 site)
Molecular
Reagents
less
  • All nucleic 9
    cDNA 9

    Microarray probesets 6
References
more
  • Summaries
    All 42
    Developmental Gene Expression 3
    Diseases 1
    Gene Ontology 3
    Phenotypes 17
  • Earliest
    J:208 Hertwig P, Neue Mutationen und Koppelungsgruppen bei der Hausmaus. Z Indukt Abstamm Vererbungsl. 1942;80(1):220-246
  • Latest
    J:326541 Cyagen Biosciences Inc., Cyagen Biosciences Website. 2022;
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/08/2026
MGI 6.24 		The Jackson Laboratory