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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID
Lama1
laminin, alpha 1
MGI:99892
51 phenotypes from 9 alleles in 7 genetic backgrounds
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Allelic Composition
Genetic Background
Annotated Term Reference
Lama1GT(PST008)Byg/Lama1GT(PST008)Byg
involves: 129P2/OlaHsd * C57BL/6
abnormal gastrulation J:91048
absent Reichert's membrane J:91048
decreased embryo size J:91048
embryonic lethality between implantation and somite formation, complete penetrance J:91048
Lama1nmf223/Lama1nmf223
C57BL/6J-Lama1nmf223/J
abnormal eye electrophysiology J:160722
abnormal Muller cell morphology J:160722
abnormal ocular fundus morphology J:160722
abnormal retina blood vessel morphology J:160722
abnormal retina blood vessel pattern J:160722
abnormal retina inner limiting membrane morphology J:160722
abnormal retina morphology J:160722
abnormal retina vasculature morphology J:160722
abnormal vitreous body morphology J:160722
persistence of hyaloid vascular system J:160722
retina spots J:160722
thin retina ganglion layer J:160722
thin retina inner nuclear layer J:160722
vitreal fibroplasia J:160722
Lama1nmf223/Lama1tm1.1Olf
involves: 129S2/SvPas * C57BL/6J
abnormal ocular fundus morphology J:160722
abnormal retina morphology J:160722
abnormal retina vasculature morphology J:160722
vitreal fibroplasia J:160722
Lama1tm1.1Arhi/Lama1tm1.1Arhi
involves: 129S1/Sv * 129X1/SvJ * C57BL/6
no abnormal phenotype detected J:184432
Lama1tm1.1Arhi/Lama1tm1.2Arhi
involves: 129S1/Sv * 129X1/SvJ * C57BL/6
no abnormal phenotype detected J:184432
Lama1tm1.1Arhi/Lama1tm1.2Arhi
Edil3Tg(Sox2-cre)1Amc/?
involves: 129S1/Sv * 129X1/SvJ * C57BL/6
abnormal Bergmann glial cell morphology J:184432
abnormal brain meninges morphology J:184432
abnormal brain pia mater morphology J:184432
abnormal cerebellar foliation J:184432
abnormal cerebellar granule layer morphology J:184432
abnormal cerebellar Purkinje cell layer J:184432
abnormal cerebellum morphology J:184432
abnormal Purkinje cell dendrite morphology J:184432
abnormal radial glial cell morphology J:184432
impaired coordination J:184432
limb grasping J:184432
normal mortality/aging J:184432
short stride length J:184432
small cerebellum J:184432
Lama1tm1.1Ekb/Lama1tm1.1Ekb
involves: 129S1/Sv * 129X1/SvJ * C57BL/6
abnormal Reichert's membrane morphology J:96100
absent blastocoele J:96100
absent Reichert's membrane J:96100
embryonic lethality between implantation and somite formation, complete penetrance J:96100
Lama1tm1.1Olf/Lama1tm1.1Olf
involves: 129S2/SvPas
abnormal ectoplacental cone morphology J:102740
abnormal parietal endoderm morphology J:102740
abnormal visceral endoderm morphology J:102740
absent Reichert's membrane J:102740
embryonic growth retardation J:102740
embryonic lethality between implantation and somite formation, complete penetrance J:102740
increased embryonic tissue cell apoptosis J:102740
Lama1tm1.2Arhi/Lama1tm1.2Arhi
involves: 129S1/Sv * 129X1/SvJ * C57BL/6
absent Reichert's membrane J:184432
embryonic lethality between implantation and somite formation, complete penetrance J:184432
Lama1tm1Ekb/Lama1tm1Ekb
involves: 129S1/Sv * 129X1/SvJ * C57BL/6
abnormal Reichert's membrane morphology J:96100
absent blastocoele J:96100
absent Reichert's membrane J:96100
embryonic lethality between implantation and somite formation, complete penetrance J:96100
Lama1tm1Olf/Lama1tm1Olf
involves: 129S2/SvPas
no abnormal phenotype detected J:102740
Lama1tm1Olf/Lama1tm1Olf
Edil3Tg(Sox2-cre)1Amc/Edil3+
involves: 129S2/SvPas * C57BL/6J * CBA * CD-1 * Swiss Webster
abnormal Muller cell morphology J:160722
abnormal ocular fundus morphology J:160722
abnormal retina blood vessel morphology J:160722
abnormal retina blood vessel pattern J:160722
abnormal retina inner limiting membrane morphology J:160722
abnormal retina neuronal layer morphology J:160722
abnormal retina vasculature morphology J:160722
decreased birth weight J:160722
macrophthalmia J:160722
normal mortality/aging J:160722
persistence of hyaloid vascular system J:160722
normal reproductive system phenotype J:160722
retina outer nuclear layer degeneration J:160722
retina spots J:160722
thin retina inner nuclear layer J:160722
thin retina inner plexiform layer J:160722
vitreal fibroplasia J:160722
Lama1tm2b(EUCOMM)Hmgu/Lama1+
C57BL/6N-Lama1tm2b(EUCOMM)Hmgu/Ieg
abnormal lens morphology J:211773
abnormal retina morphology J:211773
decreased exploration in new environment J:211773
increased circulating alanine transaminase level J:211773
increased startle reflex J:211773
persistence of hyaloid vascular system J:211773
Lama1tm2b(EUCOMM)Hmgu/Lama1tm2b(EUCOMM)Hmgu
C57BL/6N-Lama1tm2b(EUCOMM)Hmgu/Ieg
preweaning lethality, complete penetrance J:211773

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last database update
04/30/2024
MGI 6.23
The Jackson Laboratory