31 phenotypes from multigenic genotypes

Allelic Composition Genetic Background	Annotated Term	Reference
CbfbTgTn(sb-cHS4,Tyr)2512E-2Ove/CbfbTgTn(sb-cHS4,Tyr)2512E-2Ove FVB/N-CbfbTgTn(sb-cHS4,Tyr)2512E-2Ove	embryonic lethality during organogenesis, complete penetrance	J:175597
Cbfbtm1Itan/Cbfbtm1Itan Rr94tm3.1Litt/Rr94tm3.1Litt Tg(Cd4-cre)1Cwi/0 involves: 129P2/OlaHsd * C57BL/6 * DBA/2 * FVB/N	abnormal double-positive T cell morphology	J:158962
	abnormal T cell subpopulation ratio	J:158962
	decreased CD4-positive, alpha-beta T cell number	J:158962
	decreased double-positive T cell number	J:158962
	increased CD8-positive, alpha-beta T cell number	J:158962
	increased double-positive T cell number	J:158962
Cbfbtm1Itan/Cbfbtm1Itan Zbtb7btm2Litt/Zbtb7b+ Tg(Lck-cre)1Cwi/0 involves: 129P2/OlaHsd * C57BL/6	abnormal T cell differentiation	J:141144
	decreased CD4-positive, alpha-beta T cell number	J:141144
Cbfbtm1Itan/Cbfbtm1Itan Zbtb7btm2Litt/Zbtb7btm1.2Litt Tg(Lck-cre)1Cwi/0 involves: 129P2/OlaHsd * C57BL/6	abnormal T cell differentiation	J:141144
	decreased CD4-positive, alpha-beta T cell number	J:141144
Cbfbtm2.1Ddg/Cbfbtm2.1Ddg Mapttm2Arbr/? H2az2Tg(Wnt1-cre)11Rth/H2az2+ involves: 129P2/OlaHsd * 129S6/SvEvTac * C57BL/6J * CBA/J	abnormal axon morphology	J:226826
	abnormal craniofacial development	J:226826
	abnormal nociceptor morphology	J:226826
	abnormal sensory neuron innervation pattern	J:226826
	perinatal lethality	J:226826
Cbfbtm2.1Ddg/Cbfbtm2.1Ddg Mapttm2Arbr/? Runx1tm1(cre/Esr1*)Ims/? involves: 129S6/SvEvTac * C57BL/6NCrlj * CBA/JNCrlj	abnormal mechanoreceptor morphology	J:226826
Cbfbtm3Ppl/Cbfb+ involves: 129S6/SvEvTac * C57BL/6	decreased hematopoietic stem cell number	J:160522
	normal hematopoietic system phenotype	J:160522
	internal hemorrhage	J:160522
	lethality throughout fetal growth and development, complete penetrance	J:160522
	pale liver	J:160522
	postnatal lethality, complete penetrance	J:160522
	prenatal lethality, incomplete penetrance	J:160522
Cbfbtm4Ppl/Cbfb+ involves: 129S6/SvEvTac * C57BL/6	abnormal bone marrow cell morphology/development	J:160522
	absent megakaryocytes	J:160522
	pale liver	J:160522
Cbfbtm5Ppl/Cbfb+ Not Specified	abnormal mononuclear cell differentiation	J:193140
	myeloid hyperplasia	J:193140
	normal neoplasm	J:193140
Cbfbtm5Ppl/Cbfbtm5Ppl Not Specified	embryonic lethality during organogenesis, complete penetrance	J:193140
	impaired hematopoiesis	J:193140
	intracranial hemorrhage	J:193140
Cbfbtm6Ppl/Cbfb+ involves: 129S/SvEv * C57BL/6	decreased B cell number	J:252447
	normal hematopoietic system phenotype	J:252447
	increased myeloid cell number	J:252447
	normal neoplasm	J:252447
Cbfbtm6Ppl/Cbfbtm6Ppl involves: 129S/SvEv * C57BL/6	embryonic lethality, complete penetrance	J:252447
	impaired hematopoiesis	J:252447
	internal hemorrhage	J:252447