Syt2 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Syt2
synaptotagmin II
MGI:99666

19 phenotypes from 4 alleles in 4 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Syt2^m1Btlr/Syt2^m1Btlr C57BL/6J-Syt2^m1Btlr	ataxia	J:224662
Syt2^m1Btlr/Syt2^m1Btlr C57BL/6J-Syt2^m1Btlr	tremors	J:224662
Syt2^m1Ingm/Syt2^m1Ingm Not Specified	abnormal excitatory postsynaptic currents	J:108786
	abnormal miniature endplate potential	J:108786
	abnormal miniature excitatory postsynaptic currents	J:108786
	ataxia	J:108786
	decreased body weight	J:108786
	impaired coordination	J:108786
	infertility	J:108786
	prolonged excitatory postsynaptic current rise time	J:108786
Syt2^tm1Sud/Syt2^tm1Sud B6.129-Syt2^tm1Sud	abnormal CNS synaptic transmission	J:117050
	abnormal inhibitory postsynaptic currents	J:117050
	abnormal locomotor behavior	J:117050
	abnormal miniature endplate potential	J:117050
	abnormal motor capabilities/coordination/movement	J:117050
	abnormal neurotransmitter secretion	J:117050
	decreased body weight	J:117050
	decreased neurotransmitter release	J:117050
	enhanced paired-pulse facilitation	J:117050
	lethality at weaning, complete penetrance	J:117050
	postnatal growth retardation	J:117050
Syt2^tm2Sud/Syt2^tm2Sud involves: 129S6/SvEvTac * C57BL/6J	no abnormal phenotype detected	J:101977

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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