Xrcc1 Phenotype Annotations - Multigenic Genotypes

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Xrcc1
X-ray repair complementing defective repair in Chinese hamster cells 1
MGI:99137

7 phenotypes from multigenic genotypes

Allelic Composition Genetic Background	Annotated Term	Reference
Trp53^tm1Tyj/Trp53^tm1Tyj Xrcc1^tm1Rpe/Xrcc1^tm1Rpe involves: 129S2/SvPas * 129X1/SvJ	decreased embryo size	J:54226
	embryonic growth arrest	J:54226
	embryonic lethality, complete penetrance	J:54226
Xrcc1^tm1Pmc/Xrcc1^tm1Pmc Trp53^tm1Tyj/Trp53⁺ Tg(Nes-cre)1Kln/0 involves: 129S1/Sv * 129S2/SvPas * C57BL/6 * SJL	increased medulloblastoma incidence	J:152528
	premature death	J:152528
Xrcc1^tm1Pmc/Xrcc1^tm1Pmc Trp53^tm1Tyj/Trp53^tm1Tyj Tg(Nes-cre)1Kln/0 involves: 129S1/Sv * 129S2/SvPas * C57BL/6 * SJL	abnormal neuron differentiation	J:152528
	increased medulloblastoma incidence	J:152528
	normal nervous system phenotype	J:152528
	premature death	J:152528

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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