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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Xist
inactive X specific transcripts
MGI:98974
32 phenotypes from multigenic genotypes
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Allelic Composition
Genetic Background		 Annotated Term Reference
Gt(ROSA)26Sortm1(rtTA)Awu/Gt(ROSA)26Sortm1(rtTA)Awu
Xisttm1Awu/Y
involves: 129S4/SvJae 		abnormal B cell differentiation J:112954
abnormal definitive hematopoiesis J:112954
abnormal embryonic tissue morphology J:112954
abnormal erythropoiesis J:112954
abnormal myelopoiesis J:112954
abnormal T cell differentiation J:112954
abnormal thymus morphology J:112954
absent pre-B cells J:112954
anemia J:112954
decreased bone marrow cell number J:112954
decreased double-positive T cell number J:112954
decreased granulocyte number J:112954
decreased hematocrit J:112954
decreased immature B cell number J:112954
decreased macrophage cell number J:112954
decreased pro-B cell number J:112954
decreased thymocyte number J:112954
increased hematopoietic stem cell number J:112954
neonatal lethality J:112954
premature death J:112954
prenatal lethality J:112954
small thymus J:112954
thymus hypoplasia J:112954
weakness J:112954
Gt(ROSA)26Sortm1(rtTA)Awu/Gt(ROSA)26Sortm1(rtTA)Awu
Xisttm1Awu/Xisttm1Awu
involves: 129S4/SvJae 		decreased bone marrow cell number J:112954
decreased hematocrit J:112954
premature death J:112954
small thymus J:112954
weakness J:112954
Tg(CAG-EGFP)D4Nagy/0
Xisttm5.2Nbd/Xist+
involves: 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ 		abnormal dosage compensation, by inactivation of X chromosome J:171502
Tsixtm1Enl/Tsix+
Xisttm1Jae/Xist+
involves: 129S4/SvJae 		decreased embryo size J:68136
Tsixtm1Enl/Tsix+
Xisttm1Sado/Xist+
involves: 129S4/SvJae 		embryonic lethality between implantation and somite formation, complete penetrance J:99399
Xisttm5.2Nbd/Y
involves: 129P2/OlaHsd 		transmission ratio distortion J:171502
Xisttm5.2Nbd/Xist+
involves: 129P2/OlaHsd 		abnormal dosage compensation, by inactivation of X chromosome J:171502
absent placental labyrinth J:171502
decreased embryo size J:171502
embryonic growth retardation J:171502
embryonic lethality during organogenesis, complete penetrance J:171502
open neural tube J:171502
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
04/16/2024
MGI 6.23 		The Jackson Laboratory