75 phenotypes from 7 alleles in 8 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Gt(ROSA)26Sortm1(Tfrc*)Nca/Gt(ROSA)26Sortm1(Tfrc*)Nca involves: 129S4/SvJae * FVB/N	increased circulating iron level	J:133221
	increased heart iron level	J:133221
	increased liver iron level	J:133221
Tfrcem1(IMPC)H/Tfrc+ C57BL/6N-Tfrcem1(IMPC)H/H	abnormal gait	J:211773
	abnormal vocalization	J:211773
	decreased hemoglobin content	J:211773
	decreased mean corpuscular hemoglobin	J:211773
	decreased mean corpuscular hemoglobin concentration	J:211773
	decreased mean corpuscular volume	J:211773
	increased erythrocyte cell number	J:211773
	increased large unstained cell number	J:211773
	increased red blood cell distribution width	J:211773
Tfrcem1(IMPC)H/Tfrcem1(IMPC)H C57BL/6N-Tfrcem1(IMPC)H/H	embryonic lethality prior to tooth bud stage	J:211773
	preweaning lethality, complete penetrance	J:211773
TfrcMvd001/Tfrc+ C3HeB/FeJ-TfrcMvd001	decreased mean corpuscular hemoglobin	J:186868
	decreased mean corpuscular volume	J:186868
	increased erythrocyte cell number	J:186868
TfrcRbc6/Tfrc+ involves: C57BL/6	abnormal hematopoietic system morphology/development	J:330452
	decreased hematocrit	J:330452
	decreased hemoglobin content	J:330452
	decreased mean corpuscular hemoglobin	J:330452
	decreased mean corpuscular volume	J:330452
	increased erythrocyte cell number	J:330452
	increased red blood cell distribution width	J:330452
	microcytic anemia	J:330452
Tfrctm1Nca/Tfrc+ either: (involves: 129S4/SvJae * 129S6/SvEvTac) or (involves: 129S4/SvJae * C57BL/6)	abnormal erythropoiesis	J:54107
	abnormal intestinal mineral absorption	J:54107
	abnormal iron homeostasis	J:54107
	abnormal iron level	J:54107
	decreased liver iron level	J:54107
	decreased mean corpuscular hemoglobin	J:54107
	decreased mean corpuscular volume	J:54107
	decreased spleen iron level	J:54107
	normal hematopoietic system phenotype	J:54107
	increased erythrocyte cell number	J:54107
	microcytosis	J:54107
Tfrctm1Nca/Tfrctm1Nca either: (involves: 129S4/SvJae * 129S6/SvEvTac) or (involves: 129S4/SvJae * C57BL/6)	abnormal embryonic erythrocyte morphology	J:54107
	abnormal embryonic erythropoiesis	J:54107
	anemia	J:54107
	decreased erythroid progenitor cell number	J:54107
	embryo tissue necrosis	J:54107
	embryonic growth retardation	J:54107
	embryonic lethality, complete penetrance	J:54107
	hydrops fetalis	J:54107
	hypoxia	J:54107
	increased apoptosis	J:54107
	kinked neural tube	J:54107
	pallor	J:54107
	pericardial effusion	J:54107
Tfrctm2Nca/Tfrctm2Nca involves: 129S4/SvJae * FVB/N	decreased circulating iron level	J:133221
	hypochromic microcytic anemia	J:133221
Tfrctm3.1Nca/Tfrctm3.1Nca involves: 129S4/SvJae * CD-1	no abnormal phenotype detected	J:224823
Tfrctm3.1Nca/Tfrctm3.1Nca H2az2Tg(Wnt1-cre)11Rth/H2az2+ involves: 129S4/SvJae * C57BL/6J * CBA/J	abnormal gonial bone morphology	J:316198
	abnormal hyoid bone morphology	J:316198
	abnormal mandible morphology	J:316198
	abnormal mandibular angle morphology	J:316198
	abnormal Meckel's cartilage morphology	J:316198
	abnormal secondary palate development	J:316198
	abnormal suckling behavior	J:316198
	abnormal tongue morphology	J:316198
	abnormal tympanic ring morphology	J:316198
	complete cleft palate	J:316198
	failure of palatal shelf elevation	J:316198
	micrognathia	J:316198
	neonatal lethality, complete penetrance	J:316198
	oral cleft	J:316198
	respiratory distress	J:316198
	short mandible	J:316198
	small mandibular condyloid process	J:316198
	small mandibular coronoid process	J:316198
	small Meckel's cartilage	J:316198
Tfrctm3.1Nca/Tfrctm3.1Nca Tg(Vil1-cre)20Syr/0 involves: 129S4/SvJae * C57BL/6 * CD-1 * DBA/2	abnormal colon morphology	J:224823
	abnormal duodenum morphology	J:224823
	abnormal enterocyte morphology	J:224823
	abnormal enterocyte proliferation	J:224823
	abnormal intestine morphology	J:224823
	abnormal small intestine morphology	J:224823
	blunted small intestinal villi	J:224823
	decreased body size	J:224823
	decreased colon length	J:224823
	distended stomach	J:224823
	melena	J:224823
	postnatal lethality, complete penetrance	J:224823
Tfrctm3.1Nca/Tfrctm3.1Nca Tg(Vil1-cre/ERT2)23Syr/0 involves: 129S4/SvJae * C57BL/6 * CD-1 * DBA/2	abnormal enterocyte proliferation	J:224823
	blunted small intestinal villi	J:224823
	diarrhea	J:224823
	distended stomach	J:224823
	premature death	J:224823
	weight loss	J:224823